Fixation index (Fst), either per variant, or genome-wide

snp_fst(list_df_af, min_maf = 0, overall = FALSE)

Arguments

list_df_af

List of data frames with $af (allele frequency per variant) and $N (sample size per variant). Typically, the outputs of bed_MAF(). Each new data frame of the list should correspond to a different population.

min_maf

Minimum MAF threshold (for the average of populations) to be included in the final results. Default is 0 (remove monomorphic variants).

overall

Whether to compute Fst genome-wide (TRUE) or per variant (FALSE, the default).

Value

If overall, then one value, otherwise a value for each variant with missing values for the variants not passing min_maf. This should be equivalent to using '--fst --within' in PLINK.

References

Weir, B. S., & Cockerham, C. C. (1984). Estimating F-statistics for the analysis of population structure. Evolution, 1358-1370.

Examples

bedfile <- system.file("extdata", "example.bed", package = "bigsnpr")
obj.bed <- bed(bedfile)

pop <- rep(1:3, c(143, 167, 207))
ind_pop <- split(seq_along(pop), pop)
list_df_af <- lapply(ind_pop, function(ind) bed_MAF(obj.bed, ind.row = ind))

snp_fst(list_df_af)
#>    [1]  1.543045e-02 -2.169328e-03  7.547931e-02  2.005200e-02  1.341171e-02
#>    [6]  1.284776e-02 -1.668094e-03  2.863110e-02  1.310423e-02  1.028161e-02
#>   [11]  1.311446e-03  6.048104e-02  6.461257e-04  1.634420e-02  3.937796e-02
#>   [16]  9.563337e-03  1.688172e-02  2.837635e-03  8.945946e-02  2.140082e-03
#>   [21]  7.939371e-03  3.864715e-02  9.543752e-02  4.107514e-03  4.611262e-03
#>   [26]  6.951473e-03  1.549327e-02 -1.567636e-03  1.308605e-02  7.275180e-03
#>   [31]  1.835942e-02  5.585610e-02  2.632867e-02  1.644675e-02  6.363957e-03
#>   [36]  3.814747e-02  1.780071e-02  9.449087e-03  2.011848e-02  5.265473e-03
#>   [41]  5.799004e-02  1.409117e-02 -1.405625e-03  2.677332e-03  1.951528e-02
#>   [46]  7.476653e-02  5.952416e-03  2.590247e-02  2.530620e-02  4.362286e-02
#>   [51]  1.109059e-02  4.217198e-02 -2.533360e-03  3.105081e-03  3.659101e-02
#>   [56]  1.452789e-02  2.937863e-03  5.122977e-03  2.046667e-02  1.614739e-03
#>   [61]  3.020587e-02  2.672125e-02  5.414846e-03  1.455358e-02  6.170342e-02
#>   [66]  9.519266e-03  6.215310e-03  5.680548e-02  5.208650e-02  1.612086e-02
#>   [71]  1.750004e-03  3.153358e-02  5.548679e-03  1.598274e-03  6.826723e-03
#>   [76]  1.140997e-01  9.022360e-03  3.543188e-02  2.801784e-02  1.355134e-02
#>   [81] -4.846937e-04 -1.981126e-03  9.220008e-03  6.877762e-03  5.283037e-03
#>   [86]  4.601141e-03  1.489982e-02  1.028073e-02  5.217791e-02  2.671989e-02
#>   [91]  1.155474e-02  1.629665e-03  3.746158e-03  1.688092e-02  7.095841e-02
#>   [96]  8.601746e-03  1.630078e-03  4.712970e-02 -2.026861e-03  4.382426e-02
#>  [101]  8.953944e-03  8.465314e-03  1.070688e-02 -2.167495e-03  1.413617e-03
#>  [106]  1.141738e-02  4.952875e-02  3.472722e-02  4.030903e-02  1.166612e-02
#>  [111]  1.591381e-03  2.164242e-02  6.444587e-02  3.602149e-03 -2.001796e-03
#>  [116]  4.824294e-02  2.001296e-02  2.351789e-02  1.815557e-02  4.829093e-02
#>  [121] -9.660194e-04  6.085866e-04  2.361124e-03  7.889039e-03  3.868404e-04
#>  [126]  8.835638e-02  7.850825e-03  5.420457e-03  2.177450e-02  4.247229e-03
#>  [131]  5.218873e-02  1.126061e-02  1.128467e-03  4.053737e-03 -2.619171e-04
#>  [136]  4.171785e-02 -2.678681e-03  1.347832e-02  2.400632e-02  1.801969e-01
#>  [141]  7.107164e-03  5.949705e-02  2.235412e-02  4.746014e-02  2.854402e-02
#>  [146]  2.442027e-03  6.643948e-03  1.056151e-02  3.141002e-03 -6.051411e-04
#>  [151] -4.062746e-04  4.608874e-03  3.950825e-02  4.129305e-03  6.411405e-02
#>  [156]  2.955847e-02  4.409791e-03  5.129482e-03  5.637515e-02  5.008201e-02
#>  [161]  9.605688e-02  9.403817e-03  1.380743e-02  3.230157e-02  3.083386e-03
#>  [166]  5.327705e-03  6.431723e-04  2.871432e-02  9.391914e-03  3.707776e-02
#>  [171]  1.389400e-02  5.533933e-02  9.244319e-03  5.143589e-03  5.788722e-03
#>  [176]  4.032006e-03  2.225409e-02  1.234244e-01  5.216575e-03  1.294365e-01
#>  [181]  3.793093e-02  5.753108e-02 -1.738614e-03  1.063711e-02  1.109977e-02
#>  [186]  8.982627e-03  1.423283e-02  1.432678e-02 -3.133558e-04 -2.291442e-03
#>  [191]  8.356760e-02  4.605146e-02  1.421173e-02  1.629579e-02  2.235505e-02
#>  [196]  2.572724e-03  3.667041e-03  6.768676e-02  2.800116e-02  2.392317e-03
#>  [201]  1.871958e-02  1.395687e-02  6.047524e-02  3.534494e-02  7.582991e-03
#>  [206]  8.200136e-03  8.683916e-03 -1.530130e-03  3.448685e-02  5.819651e-02
#>  [211]  1.883411e-02  1.150014e-02  1.409665e-01  4.376772e-03  3.451263e-02
#>  [216]  3.442576e-02  2.719865e-02  2.695164e-02  1.180838e-02  1.929607e-02
#>  [221]  1.985359e-01  2.546878e-03  8.757389e-03 -3.280835e-04 -7.522644e-04
#>  [226]  2.284250e-02  4.380814e-03  2.167918e-03 -2.236463e-03  2.568060e-02
#>  [231]  3.558835e-02  1.108389e-02 -2.871977e-04 -8.989426e-04  4.874745e-02
#>  [236]  8.400014e-03  1.095682e-02  4.791152e-02  7.028391e-03  1.987341e-03
#>  [241] -1.267478e-03  8.810417e-03 -2.826245e-03  1.109485e-01  2.437305e-02
#>  [246]  3.395624e-02  2.773837e-02  1.996593e-02  4.431159e-02  9.380416e-02
#>  [251] -1.507605e-04  8.780172e-03  5.403270e-03  2.982505e-02  6.875635e-03
#>  [256]  9.783343e-02  3.697928e-02 -1.288126e-03  6.069391e-02  3.455663e-03
#>  [261]  5.984329e-02  3.616606e-03  1.088731e-02  8.871933e-03  3.024430e-02
#>  [266]  1.512484e-01 -8.184125e-04  1.080811e-02  6.755763e-03  4.470558e-02
#>  [271]  9.424588e-02  4.365987e-03  1.358421e-02  1.437852e-02  4.577823e-02
#>  [276] -2.056149e-03  1.976063e-02  5.596134e-02  1.307421e-04  4.186544e-02
#>  [281]  7.653015e-03 -1.273900e-03  1.382540e-02  3.908506e-02  1.589177e-02
#>  [286]  5.764979e-02  4.183202e-02  9.977312e-03  8.786411e-03  3.162945e-03
#>  [291]  9.681632e-03 -1.493183e-03  1.569978e-02  3.069650e-02  4.339903e-03
#>  [296]  5.015502e-02  2.255641e-02  3.744071e-03 -1.635994e-04  2.784051e-02
#>  [301] -1.261188e-03  2.238103e-02  4.847429e-02  8.575091e-03  3.390729e-03
#>  [306]  8.264379e-03  6.654695e-03 -7.582156e-04  9.769377e-03  1.013085e-02
#>  [311]  2.710287e-02  1.227956e-02  2.174382e-02  3.095358e-02  2.206656e-03
#>  [316]  3.034289e-02  6.944915e-02 -2.912749e-03  7.011993e-02  5.498200e-02
#>  [321]  5.051094e-03  8.760345e-03  2.011211e-02  7.839928e-03  1.311068e-02
#>  [326]  9.048597e-03  4.223633e-02  1.336765e-02  1.531634e-02  1.833969e-02
#>  [331]  1.170398e-03 -2.028195e-03  6.340619e-02  6.245837e-04  2.266373e-02
#>  [336]  1.797782e-02  1.013804e-02  1.968546e-02  3.663117e-02  1.958433e-02
#>  [341]  1.189087e-02  3.802859e-02  2.163405e-02  1.709351e-03  5.433161e-03
#>  [346]  6.917241e-04  4.084615e-03  1.625560e-02  4.800492e-03  5.532535e-02
#>  [351]  4.230085e-03  3.234814e-02  1.781018e-02  1.186013e-02 -1.880157e-03
#>  [356]  5.852492e-02  3.809045e-02  3.417876e-03 -2.197629e-03 -2.382627e-03
#>  [361]  6.951122e-03  7.572571e-03 -2.707061e-03  3.925299e-02  6.630972e-03
#>  [366]  1.445965e-02  3.560618e-02  2.924725e-02 -2.383900e-03 -9.906435e-04
#>  [371]  1.055309e-02  8.138047e-02  1.155591e-03  1.157838e-02  3.272190e-03
#>  [376] -2.856743e-04  1.828469e-02  2.391620e-03  8.463414e-02  4.802689e-02
#>  [381]  5.019031e-02  9.624627e-03 -2.402689e-03  1.011823e-01  2.326184e-02
#>  [386]  2.728496e-02  1.018166e-01  8.482023e-04  3.581413e-02  1.002541e-01
#>  [391]  4.354375e-02  1.051153e-01  6.334074e-02 -9.890657e-04  2.963291e-03
#>  [396]  2.372193e-03  3.963791e-03  8.718445e-02  2.389141e-02  2.278803e-02
#>  [401]  3.243822e-02  1.683110e-02  1.365947e-02  2.414666e-02  1.996808e-02
#>  [406]  2.384036e-02  2.763144e-02  4.224813e-02  7.613121e-04 -1.144584e-03
#>  [411]  5.392849e-02  9.991040e-02  1.264106e-03  1.098759e-02  2.364367e-03
#>  [416]  5.650635e-03  1.230044e-02  2.772576e-02  8.287086e-03  6.083509e-02
#>  [421] -1.072968e-03  3.595946e-02 -4.456035e-04  3.126825e-02  6.001797e-04
#>  [426]  2.000784e-02  1.061202e-02 -1.979013e-04  1.935125e-02 -1.514261e-03
#>  [431]  1.822940e-02  4.781886e-02  6.625977e-03  2.562588e-02  1.184335e-02
#>  [436]  6.663707e-03  4.595120e-02  1.333663e-03  1.101094e-02  1.332642e-02
#>  [441]  3.311073e-02  3.385097e-03  6.989597e-03  1.740777e-02 -1.317866e-03
#>  [446]  5.003736e-02  1.336827e-02  8.342120e-03  5.772115e-02  3.365198e-02
#>  [451]  1.137388e-03  1.015947e-02  8.563727e-02  1.930811e-02  2.144339e-02
#>  [456]  4.801009e-03  7.043883e-03  5.289785e-03  1.250694e-02 -7.731300e-04
#>  [461]  3.660338e-03  1.184442e-02  2.295819e-02  2.557979e-03  1.679236e-02
#>  [466]  2.968423e-02  3.896377e-03 -4.471669e-04  9.823778e-02  4.022636e-02
#>  [471]  2.262438e-02  4.498119e-04  4.480231e-02  1.940306e-02  9.912843e-03
#>  [476]  4.451402e-02  4.224738e-02  1.076923e-02  4.287356e-02  6.623972e-03
#>  [481]  3.659132e-02  4.108131e-02  3.010129e-03  6.913402e-04  5.020938e-02
#>  [486]  7.814019e-04  4.880081e-03 -2.743694e-03 -5.664948e-04  4.503357e-02
#>  [491] -1.913321e-03  3.202631e-03  2.196046e-03 -1.638501e-03  5.010171e-02
#>  [496] -1.872277e-03  2.462814e-03  1.231148e-02  4.965526e-02  4.646971e-02
#>  [501]  3.190097e-03 -3.066064e-04  8.743072e-03  1.590805e-02  5.768504e-02
#>  [506]  1.818138e-02  2.765177e-03  2.404717e-02  5.202041e-02  1.026788e-01
#>  [511] -1.254748e-03  5.503284e-04  2.455699e-02  2.205036e-02  2.269116e-02
#>  [516]  2.042573e-02  3.398792e-02  8.186028e-03  4.726229e-02 -1.068849e-03
#>  [521]  1.498355e-02  1.729380e-03  1.461935e-03  2.154462e-02  2.747723e-03
#>  [526]  5.980886e-03 -1.633809e-03  2.173947e-02  2.962483e-03 -1.655813e-03
#>  [531]  6.933464e-03 -2.882314e-03  4.362349e-02  1.066311e-01 -1.844795e-03
#>  [536]  7.487712e-03  5.059379e-03  9.388172e-03  3.863858e-02  5.084047e-03
#>  [541]  3.147301e-02  2.147203e-02  5.334224e-02 -7.450134e-04  4.387218e-03
#>  [546]  6.674685e-02  1.173336e-02  3.988125e-03  2.471402e-02  4.446787e-02
#>  [551]  1.541699e-02  6.566109e-03  2.410597e-03  1.372657e-02  1.063171e-02
#>  [556]  1.870833e-03  3.371751e-02  5.838469e-03  4.361866e-02  1.126297e-02
#>  [561]  2.835101e-03  1.387574e-02  2.202621e-02  3.452827e-02  2.309395e-02
#>  [566]  1.340440e-02  9.254837e-02  9.933884e-05  3.875916e-02  4.803562e-03
#>  [571]  1.945722e-02  6.479027e-06  3.222356e-03  1.015814e-02  3.144923e-02
#>  [576]  1.447602e-02  2.461977e-03  9.430122e-03  5.174070e-03  6.050421e-03
#>  [581] -9.586149e-04  3.383618e-02  4.554634e-03  4.320448e-02  1.206898e-03
#>  [586]  4.251959e-03  6.472484e-02  1.505182e-02  2.873995e-03 -2.494308e-03
#>  [591]  7.249728e-02  4.632950e-02  2.948519e-02  4.576753e-02  1.761854e-03
#>  [596]  2.968336e-02  2.273200e-02  1.525543e-02  1.768396e-02  1.625855e-03
#>  [601]  3.760383e-02  3.415192e-02  1.566402e-02  3.860343e-02  7.698836e-02
#>  [606] -2.726238e-03  1.634832e-02  2.233333e-02  7.616938e-02  1.320531e-02
#>  [611]  2.439182e-02  1.377137e-02  6.826569e-03  3.472230e-02  3.870303e-02
#>  [616] -9.367197e-04  1.404071e-02  4.137755e-03  8.713934e-03  8.856235e-03
#>  [621]  7.521700e-03  3.252444e-03 -1.220817e-03  1.598740e-02  3.297560e-02
#>  [626]  3.205072e-02 -1.163780e-03  4.021618e-02  2.162010e-02  7.411412e-03
#>  [631]  4.166064e-04  3.708722e-02  6.898382e-02  1.994149e-02  7.948726e-03
#>  [636]  2.249441e-03  8.459664e-03  3.279634e-03  1.736390e-03  1.794839e-02
#>  [641]  3.369846e-02  6.496992e-03  1.103478e-01 -2.416046e-03  1.189682e-02
#>  [646]  1.829453e-03  5.953225e-03  3.116972e-03  4.311550e-03  2.516685e-02
#>  [651]  3.109018e-04  1.634593e-01  1.043141e-02  4.147931e-02  2.888133e-02
#>  [656]  1.412929e-02  1.541965e-02  5.467886e-03  1.217982e-01  4.244131e-02
#>  [661]  2.472883e-02  3.073355e-02  5.711972e-02  2.936236e-03  2.815323e-03
#>  [666]  4.681286e-02  1.871021e-02  7.210541e-03 -1.131915e-03 -5.193434e-04
#>  [671]  1.585266e-01 -2.452012e-03  1.125622e-02  2.219406e-02  1.315475e-03
#>  [676]  9.890966e-02  7.509849e-02  4.993597e-02  8.588069e-03 -1.053985e-03
#>  [681]  1.315308e-03  2.075884e-02  2.660986e-02  6.137550e-03  4.784682e-02
#>  [686]  9.699993e-03  3.411142e-02  4.606148e-03  1.201645e-01  9.675528e-02
#>  [691]  2.362703e-02  7.629146e-04  1.530470e-02  2.795979e-02  3.207271e-02
#>  [696]  6.178708e-03  1.057816e-02  9.937529e-02  7.052417e-03  1.339710e-02
#>  [701]  1.363332e-01  1.171364e-03  5.492111e-02  6.320041e-02  3.370412e-02
#>  [706]  5.343815e-02  9.598165e-03  5.196212e-02  8.827428e-03  3.006486e-02
#>  [711]  3.279345e-02  4.952755e-02  1.382553e-02  2.730495e-03 -1.108414e-03
#>  [716]  1.952194e-02  3.996887e-02  4.325485e-03  7.439307e-03  4.001991e-03
#>  [721]  6.941063e-02  8.078724e-03  5.982802e-02  5.582526e-02  3.593856e-02
#>  [726] -2.678608e-04  7.575026e-03 -2.929292e-04  7.900900e-06  3.731450e-02
#>  [731] -3.321079e-04  8.508428e-03  4.129712e-02  6.367515e-03  4.692952e-02
#>  [736] -5.589517e-04  5.096984e-03  4.584820e-03  1.021275e-02  1.412424e-03
#>  [741]  8.067718e-03  1.201976e-01  7.842269e-03 -2.239890e-03  4.368728e-03
#>  [746]  1.703876e-02  3.668580e-03  3.255302e-02  2.373535e-02  5.593272e-02
#>  [751]  5.797778e-03 -2.931211e-03  4.183550e-03  5.798186e-02  1.303355e-02
#>  [756]  2.181900e-02  5.853789e-02  3.254843e-03  1.584315e-02  9.704243e-03
#>  [761]  2.101045e-02  1.031508e-02  2.886908e-02  4.846609e-03  3.430506e-02
#>  [766]  2.496477e-02  5.338302e-03  1.102856e-04  3.697424e-02  4.816986e-02
#>  [771]  3.666124e-02  5.948119e-03  1.566604e-02  3.317126e-02  1.678946e-02
#>  [776]  2.245571e-02  4.336414e-02  1.081510e-02  4.434306e-03  1.394085e-02
#>  [781]  9.117850e-02  5.554289e-02  2.063539e-02 -1.173027e-03  1.154323e-02
#>  [786]  4.841347e-02  6.955475e-02 -1.429300e-03  2.191287e-02  2.501021e-02
#>  [791]  3.111548e-02  4.190206e-02 -1.123578e-03  3.829729e-04  9.824666e-02
#>  [796]  6.222118e-02  2.476344e-02  1.637001e-02  1.342672e-02  1.820236e-02
#>  [801]  5.600523e-02  1.868593e-02  2.215156e-02  2.441409e-02  2.354089e-02
#>  [806] -4.964489e-04  1.316618e-02  1.264247e-02  9.890868e-03  5.095005e-03
#>  [811]  3.519277e-02  1.736723e-02  7.207533e-02  9.437562e-03  2.681100e-02
#>  [816]  5.487865e-03  6.648768e-03  5.719452e-02  3.751191e-02  2.237163e-02
#>  [821]  6.911545e-02  3.053529e-02  3.415417e-02  1.436452e-02  3.203126e-02
#>  [826] -6.324336e-04  5.740768e-02  1.281185e-02  7.548231e-02  2.561466e-03
#>  [831]  1.337403e-03  3.893380e-03  7.235299e-02  7.130514e-02  2.398139e-03
#>  [836]  3.919784e-02  1.355147e-02 -1.174914e-03  1.960236e-02  1.985183e-02
#>  [841]  6.067771e-03  7.437206e-03  5.147396e-03 -9.531571e-04  8.337285e-03
#>  [846]  4.131108e-02  2.641980e-02  4.061038e-02  1.110142e-02  8.242998e-02
#>  [851]  1.102130e-02 -5.592980e-04  4.897506e-02  2.340675e-02  1.889022e-02
#>  [856]  2.551705e-02  3.618933e-03  5.965701e-02  6.182760e-02  1.175781e-02
#>  [861]  2.178018e-02  5.749608e-02  1.781282e-02 -1.435100e-03  3.296066e-02
#>  [866]  2.943148e-02  1.576909e-02  1.906759e-03  1.361796e-02  6.972170e-02
#>  [871]  1.721319e-02  1.297906e-02  1.574199e-02  7.371475e-03 -1.416767e-03
#>  [876] -2.848018e-03  8.099110e-02 -2.286942e-03 -2.434252e-03  8.997257e-03
#>  [881]  7.829296e-03  4.629508e-02  6.043215e-02  4.455510e-02  3.845049e-02
#>  [886]  6.745874e-02  8.809777e-03  7.545891e-02  7.105008e-02  1.152231e-02
#>  [891] -1.166807e-03  2.807723e-02  3.915173e-03 -7.501257e-04  1.175113e-02
#>  [896]  8.190064e-03  4.115556e-02  1.638020e-01  9.364290e-02  2.894622e-02
#>  [901]  3.931526e-03  1.953431e-02  6.375480e-03  1.488556e-02  7.468057e-03
#>  [906]  3.426595e-03  8.323906e-04 -3.708908e-06  4.331897e-02  1.407433e-03
#>  [911]  6.520714e-02  6.203298e-02  2.180090e-04  2.041670e-02  8.161064e-02
#>  [916]  4.491545e-04  2.780534e-02  1.924889e-02 -2.300743e-03  3.504972e-04
#>  [921]  1.048646e-01  8.403908e-03  1.703690e-02  1.911679e-03 -2.355838e-03
#>  [926]  2.746375e-02  4.362861e-02  1.270805e-02  3.628128e-02  4.414338e-03
#>  [931]  6.182220e-03  6.949658e-03  7.499062e-02  1.361905e-02  5.177962e-02
#>  [936]  1.314723e-02  4.755747e-02  4.420277e-03  3.697148e-02  8.743751e-03
#>  [941]  2.339681e-02  2.895605e-03  6.750306e-02  4.108655e-02  2.095845e-02
#>  [946]  5.759781e-04  4.705716e-02  9.817240e-03  4.807146e-03  8.815020e-03
#>  [951]  3.448992e-02  3.675605e-02  1.023713e-02  1.802936e-02  4.469335e-02
#>  [956]  1.141106e-02 -7.285821e-04  3.227330e-03  7.824282e-02 -1.192825e-03
#>  [961]  1.147224e-02  9.973598e-03  4.868182e-04  9.127375e-02  3.478350e-02
#>  [966]  3.608321e-02  1.637785e-03  1.873248e-02  4.114072e-02  3.115520e-02
#>  [971]  2.699016e-02  1.504992e-02  2.722525e-02  2.145451e-03  1.781823e-02
#>  [976]  1.739919e-02 -3.896657e-04  1.790709e-02  1.942478e-02  3.644875e-02
#>  [981]  1.955483e-03  2.315273e-02  7.018259e-02  3.345703e-03  1.277124e-02
#>  [986]  3.906823e-02  9.722028e-03  5.739880e-03  1.091296e-03  1.802462e-02
#>  [991] -2.679538e-03  7.608045e-04  5.416629e-03  2.288111e-02  1.963162e-03
#>  [996]  2.779209e-02  2.246352e-02  2.653696e-02  1.570646e-02  1.992118e-02
#> [1001]  1.411182e-02  2.001999e-02  1.597317e-02  4.976317e-02  3.304040e-02
#> [1006] -2.472821e-03  4.958987e-02  1.091869e-02  2.113959e-03  1.863545e-03
#> [1011]  3.602945e-02  7.134914e-03  4.125171e-02 -9.196653e-04 -7.942579e-04
#> [1016] -1.153372e-03  6.878744e-03  1.662202e-04  1.717371e-02  7.241914e-02
#> [1021]  4.502557e-03  3.444080e-04 -2.209267e-03  2.617845e-03 -1.925526e-03
#> [1026]  1.266553e-02  5.746242e-02  7.061164e-03  1.141728e-01  4.395691e-02
#> [1031]  3.732986e-04  4.787697e-05  6.104413e-02  2.464326e-02  1.360739e-02
#> [1036]  1.825017e-02  4.626014e-02  1.402017e-02  1.602299e-02  4.452665e-03
#> [1041]  8.131922e-03  1.247614e-02  5.256360e-02  4.630535e-02  3.352912e-03
#> [1046]  1.049215e-02  4.274265e-03 -9.020313e-04 -8.423409e-04  2.052413e-02
#> [1051]  3.209308e-02 -2.862568e-03  1.419026e-02 -2.029748e-03  6.731259e-02
#> [1056]  6.535130e-03 -2.779421e-03  3.584501e-02  5.981707e-03  2.656302e-02
#> [1061]  1.677672e-02  6.613791e-02  7.318358e-04  4.846600e-03  9.026603e-03
#> [1066] -2.395166e-03  7.407523e-05  1.429881e-02  1.965768e-02  4.314109e-02
#> [1071]  1.273464e-01  9.433469e-03  2.643750e-02 -2.704341e-03  1.324859e-01
#> [1076]  5.634749e-02 -1.152844e-03  2.820397e-02  2.027329e-03  2.051504e-03
#> [1081]  5.932100e-03  2.751049e-02  3.908686e-02  3.287021e-03  7.086141e-03
#> [1086]  5.130999e-02  3.092303e-02  1.148264e-03  4.180307e-03  1.440169e-03
#> [1091]  6.323125e-02  3.737083e-02  3.057361e-02  7.710058e-03  4.218745e-03
#> [1096]  1.363328e-02  7.985839e-03  3.788459e-02 -1.961956e-03  1.123555e-02
#> [1101]  4.288980e-03  2.497810e-02  3.461381e-03  1.752372e-02  5.591849e-02
#> [1106] -1.478145e-03 -2.461877e-03  3.923395e-02  2.916094e-02  3.693106e-02
#> [1111]  2.620468e-02  1.466275e-02  7.973490e-02  8.221602e-04  8.598072e-03
#> [1116]  5.606736e-02  7.083237e-03 -1.974602e-03 -3.577668e-04  2.398977e-02
#> [1121]  1.383975e-01  3.261349e-02  6.013715e-02  1.011017e-02  7.096147e-02
#> [1126]  9.854714e-03  1.289416e-02  1.117126e-02 -2.317803e-03  4.180923e-02
#> [1131]  5.610087e-03  1.914762e-02  4.217317e-02 -2.313909e-03  1.323589e-02
#> [1136]  5.153835e-02  7.618008e-02  7.307364e-03 -2.077299e-03  3.131631e-03
#> [1141]  2.904388e-04  1.152869e-01  2.706555e-03  5.981368e-03  1.219187e-02
#> [1146]  1.476520e-02  1.713467e-02  1.556485e-02  6.043573e-02  1.893984e-02
#> [1151] -1.567630e-03  3.610983e-02  2.302548e-02  6.083539e-02 -2.229239e-03
#> [1156]  2.501686e-02  1.235170e-04  4.805560e-03  2.377291e-02  9.598452e-03
#> [1161]  1.316082e-02  1.836632e-02  6.436920e-03  2.926646e-03  1.243897e-02
#> [1166]  2.824590e-03  3.694248e-03  4.742529e-03  2.519305e-02  3.173374e-02
#> [1171]  1.272661e-03  1.543762e-02  3.251348e-02  2.371496e-02 -1.053328e-03
#> [1176]  9.101904e-02  1.404308e-02  3.865548e-02  9.851578e-03  4.457266e-02
#> [1181]  8.551015e-03  8.455242e-02  2.576406e-02  9.753898e-02  1.739563e-01
#> [1186]  9.838232e-03  1.818950e-02  6.253837e-04  2.719648e-02  1.486225e-02
#> [1191]  7.582280e-03  6.056773e-02  2.809263e-02  7.780880e-02  2.523603e-02
#> [1196]  2.881269e-02  1.238844e-02  5.628053e-03  1.565828e-02 -2.589679e-03
#> [1201]  4.452365e-02  4.180176e-02  4.582421e-02  1.551435e-02  2.837455e-02
#> [1206]  1.173041e-02  2.107829e-02  7.440692e-03 -6.853683e-04  3.293745e-03
#> [1211] -7.201921e-04  3.095877e-03 -2.631283e-03  1.416813e-04 -1.867413e-04
#> [1216]  5.701133e-03  2.107022e-02  8.019769e-03 -7.823596e-04  2.750315e-02
#> [1221]  1.651633e-02  2.274276e-02  1.967821e-02 -1.101966e-03  4.448813e-02
#> [1226]  5.155328e-03  3.988328e-02 -1.744420e-03  7.495782e-03  1.975841e-02
#> [1231] -4.832223e-04  1.106713e-02  5.555343e-02  2.208655e-02  3.532806e-02
#> [1236] -9.840787e-04  2.539340e-02  6.551643e-02  3.864442e-03  3.804068e-03
#> [1241]  6.321068e-02  7.345701e-02  2.135001e-02  1.628988e-02  8.668764e-03
#> [1246]  1.049592e-02  1.320090e-02  1.104548e-02  9.989419e-03 -5.878151e-04
#> [1251]  4.934187e-02  3.199512e-03  1.442893e-02  6.070665e-02 -4.205513e-04
#> [1256]  1.376484e-02  1.077627e-01  9.409848e-03  1.362912e-03  7.448869e-02
#> [1261]  4.632903e-02 -2.633383e-03  3.885372e-03  3.658843e-02  1.765924e-02
#> [1266]  3.602084e-03 -1.364395e-03  1.361508e-02 -1.279844e-03  1.621094e-01
#> [1271]  1.403760e-03  1.956861e-02  1.112781e-02  1.064252e-01  2.727458e-02
#> [1276] -2.462486e-03  1.269251e-02  8.966256e-03  3.541528e-03  3.863561e-03
#> [1281]  3.135674e-03  6.958640e-03  3.655337e-03  1.310912e-02  1.091422e-01
#> [1286]  1.386768e-02  6.001963e-02  4.792881e-02  6.952271e-02  1.954346e-03
#> [1291]  2.986445e-02  1.218316e-02  3.044909e-02  2.651130e-02  2.586022e-03
#> [1296]  5.023622e-03 -7.666428e-04  1.921613e-02 -1.742883e-03  3.480450e-03
#> [1301]  8.857546e-03  2.944850e-02  1.740281e-02  4.662296e-03  1.892296e-02
#> [1306] -1.972766e-03  1.252434e-01  1.068724e-02  1.676206e-04  5.762073e-03
#> [1311]  1.229415e-02  9.144848e-03  9.104086e-03  6.823408e-02  3.046806e-02
#> [1316]  2.741047e-03  1.072967e-02  1.285709e-02  2.564314e-02  2.672426e-02
#> [1321]  3.256873e-02  3.483037e-03  3.256863e-02  3.503090e-03  8.659620e-02
#> [1326]  8.400560e-03 -3.224940e-04  8.583755e-03  1.647462e-03  2.019186e-02
#> [1331]  5.297901e-02  3.035887e-02  3.889660e-03  1.263518e-02  4.311817e-02
#> [1336]  2.142284e-02  7.660469e-02  3.483960e-02  6.821648e-02  1.558431e-01
#> [1341]  2.674700e-05  2.271161e-02  9.575963e-03  8.405364e-04  1.548578e-02
#> [1346]  7.514670e-03  1.943655e-02  6.513595e-03  5.152389e-03  6.779316e-04
#> [1351]  9.664269e-03  8.500810e-03  3.597784e-02 -2.618083e-03  1.901255e-03
#> [1356]  2.230386e-02  1.372981e-02  6.666716e-03  1.072057e-02 -4.825216e-05
#> [1361]  3.953234e-02  7.417118e-03  5.121012e-02  6.690231e-02  8.787888e-03
#> [1366]  7.413778e-04  7.083848e-03  4.345574e-02  5.065017e-02  4.766843e-03
#> [1371]  5.905909e-03  1.030292e-02  1.652971e-02  7.013226e-03  1.719627e-02
#> [1376]  1.037308e-02  3.609191e-04  3.699248e-02  1.645357e-02  5.404034e-02
#> [1381]  2.031277e-02  1.450766e-02 -1.228197e-03  8.065367e-02  3.359881e-02
#> [1386]  1.046636e-01  2.554062e-02  3.357907e-03  1.406593e-03  1.594533e-02
#> [1391]  3.759364e-02 -2.590875e-03  4.787187e-02  9.204121e-03  5.185690e-02
#> [1396]  6.819184e-02 -1.180735e-05  8.546020e-03  5.295780e-02  7.560164e-03
#> [1401] -1.519522e-03  6.847313e-03  9.529183e-03  1.064083e-01  4.151775e-02
#> [1406]  1.176667e-02 -2.930369e-03  3.053360e-04  8.833461e-04  1.197120e-02
#> [1411]  8.727244e-03  2.055693e-02  1.244195e-02  1.981731e-02  5.915245e-02
#> [1416]  6.247924e-04  3.646472e-03  2.790726e-03  2.583664e-02  1.052977e-02
#> [1421]  8.533492e-04  1.734676e-03  1.310091e-02  3.580002e-02  6.268321e-02
#> [1426]  1.204405e-02 -2.581700e-03  8.581901e-03  3.032650e-02  2.504892e-03
#> [1431]  7.207699e-03  5.502039e-02  3.207421e-02  5.247676e-04  4.135530e-02
#> [1436]  5.219335e-03  1.938499e-02  1.184797e-03  3.325057e-02 -6.314375e-04
#> [1441]  2.074782e-02  6.790228e-02 -4.058829e-04  8.011944e-03  3.184933e-02
#> [1446]  8.509511e-03  2.152549e-02  1.081387e-01  7.211530e-03  1.514855e-01
#> [1451]  1.568673e-02  2.299941e-02  1.108533e-02  2.134361e-02 -4.015617e-04
#> [1456]  1.253595e-02  6.866523e-04  4.251309e-03 -1.031170e-03  2.231914e-02
#> [1461]  8.646518e-03  3.452451e-02  1.645452e-02  2.286955e-02  2.688586e-02
#> [1466]  1.599456e-02  5.553755e-03  6.864253e-02  1.972576e-02  1.968985e-03
#> [1471]  4.994498e-02  7.378125e-03  5.566191e-04  1.221900e-01  1.856310e-02
#> [1476]  6.592165e-02  1.470137e-02  1.280883e-02  6.013905e-03  3.906879e-03
#> [1481]  6.198716e-03 -2.642826e-03  3.372007e-03  8.303570e-03 -1.360552e-03
#> [1486]  3.012329e-02  1.838407e-02  1.464551e-02  6.314780e-02  1.913406e-03
#> [1491]  2.519309e-02  8.061665e-02  4.665886e-03  2.242937e-02 -5.504006e-04
#> [1496]  3.102527e-02  1.802565e-02  3.618574e-02  1.802323e-02  3.847760e-02
#> [1501]  1.383767e-02  6.337170e-02 -1.422263e-03  6.577679e-04  2.423829e-02
#> [1506]  6.446988e-02  1.646847e-02  5.274830e-04  1.861901e-02  2.621358e-03
#> [1511]  4.523665e-03  3.016508e-05  7.022394e-03  1.414870e-02  1.554316e-02
#> [1516] -1.471467e-03  5.907596e-03  3.562916e-02  2.321613e-02  5.402821e-02
#> [1521]  2.720846e-02  1.068311e-02  1.445018e-02  2.818272e-02  3.811114e-02
#> [1526]  1.076871e-02  1.989831e-03  3.094949e-02  2.130109e-02  2.477436e-02
#> [1531] -5.489134e-05 -3.562687e-04  2.992767e-02  1.522670e-01  3.588671e-05
#> [1536]  1.287868e-02 -2.551749e-04  1.587271e-02  8.949139e-04  1.303836e-02
#> [1541]  9.538892e-03 -9.666623e-04  2.284057e-02  4.985859e-03  5.906963e-02
#> [1546]  1.629947e-02  1.220843e-02 -1.587475e-03  1.223335e-02  1.266830e-02
#> [1551]  2.356400e-02  2.842463e-03  2.714941e-03  6.544546e-03  2.824471e-03
#> [1556]  4.819210e-03  9.275122e-03  3.435386e-02  9.688223e-03  7.146864e-02
#> [1561]  2.125194e-02  2.989029e-02  1.115311e-03  2.954376e-02  9.725996e-03
#> [1566]  6.493435e-03  3.515330e-02  3.098092e-02 -2.634939e-03  8.708371e-03
#> [1571]  3.034686e-02  2.051915e-02  2.730519e-02  6.450281e-03  2.218231e-03
#> [1576]  9.439125e-03  2.952077e-02  1.088635e-02  1.930093e-02 -2.866191e-03
#> [1581]  3.366767e-03  2.561383e-02  4.669950e-03  3.214629e-02 -4.326271e-04
#> [1586]  1.595813e-03  2.725821e-03  8.351327e-03  2.679640e-03  1.582687e-02
#> [1591]  1.927915e-02  8.863226e-03  1.550578e-02  8.419054e-04  7.735965e-03
#> [1596]  1.256906e-03  2.057288e-02  1.206532e-02  2.899365e-03  1.608771e-02
#> [1601]  1.197413e-02  2.554701e-02  2.379974e-02  4.094742e-03  5.077623e-02
#> [1606]  5.819700e-02  3.393396e-02  1.365295e-02  2.063941e-02  1.380102e-02
#> [1611]  4.936225e-02  1.932620e-02  1.262128e-01 -1.114619e-03  4.400207e-02
#> [1616]  1.424574e-02  2.547073e-03  8.764415e-02  8.518166e-03  5.641255e-02
#> [1621]  1.525851e-02  7.190631e-03  8.924215e-04  3.349606e-03  1.851442e-02
#> [1626]  1.116755e-02  3.082737e-02  1.000420e-02  1.825348e-01  3.923585e-03
#> [1631]  8.758391e-04  9.739562e-02  1.086040e-02  3.233202e-02 -7.846959e-04
#> [1636]  2.270090e-02  4.854709e-03 -2.143735e-03 -1.858203e-03  6.843918e-03
#> [1641] -8.087787e-04  4.486951e-02  1.907077e-02  4.341469e-02  1.316197e-02
#> [1646]  5.950724e-02  1.759420e-02  1.712291e-02  3.334360e-02  9.514945e-02
#> [1651]  2.482459e-03  3.703720e-03  1.565824e-02 -5.663537e-04  3.449251e-03
#> [1656]  5.849776e-03  2.478867e-03  1.772881e-02  2.419005e-02  8.001071e-02
#> [1661]  3.241869e-03  1.575082e-02 -2.834549e-04  2.991592e-02  1.169892e-02
#> [1666]  1.489053e-02  6.932832e-02  6.594128e-03 -2.525598e-03  1.196014e-02
#> [1671]  5.338886e-03  3.014551e-02  1.459928e-02  3.566958e-02  4.975412e-03
#> [1676]  2.612489e-03  5.383732e-02  3.010350e-03  9.468189e-03  3.697120e-02
#> [1681] -1.707867e-03  1.396339e-02  2.142856e-02  1.219834e-02  1.341580e-02
#> [1686]  1.549454e-03  1.723480e-02 -1.384645e-03 -2.497226e-03  1.103820e-02
#> [1691]  3.205250e-02  6.613726e-02  3.012064e-03 -1.136785e-03  2.980365e-02
#> [1696]  7.924027e-03 -2.445072e-03 -1.178620e-03 -2.268626e-03  6.287315e-02
#> [1701] -1.748844e-03  3.124440e-02  1.414471e-01  4.956924e-03  3.329116e-02
#> [1706]  5.908080e-03  6.123676e-03  6.503801e-03 -2.114123e-03  4.185519e-02
#> [1711]  1.717220e-02  2.620574e-02  2.921746e-02  3.986324e-03  4.927470e-03
#> [1716]  6.986270e-02 -2.428998e-03  2.873429e-02  3.058212e-03  2.853581e-02
#> [1721] -4.204910e-04  4.553319e-03  7.963369e-03  4.756526e-02  4.576071e-02
#> [1726]  5.739502e-02  4.672170e-02  1.652155e-02  6.455933e-03  9.898717e-03
#> [1731]  1.744261e-02 -1.897166e-03  6.995544e-02 -1.108311e-03  5.485441e-02
#> [1736]  2.325503e-02  2.076809e-02  1.389909e-02  5.056040e-02 -2.571354e-03
#> [1741]  1.847460e-02  2.882462e-02  1.991507e-02  7.040998e-04  1.362220e-02
#> [1746]  1.671866e-02  2.648599e-03  1.374247e-01  1.974278e-02  3.534213e-02
#> [1751] -2.026146e-03  1.051333e-02  9.452871e-03  5.819216e-02  9.018341e-03
#> [1756]  4.760125e-02  1.668445e-02  4.170146e-02  9.724560e-03  3.636268e-02
#> [1761]  3.053757e-02  1.120693e-01  3.291408e-02  4.949686e-02  2.340824e-02
#> [1766]  3.221675e-03  2.657460e-02 -2.128095e-03  3.585764e-02  3.848444e-02
#> [1771]  6.811227e-03  1.956391e-02  6.630151e-02  7.636286e-03  2.373967e-03
#> [1776]  1.658033e-02  8.698001e-04  8.525581e-04  1.761250e-02  3.025173e-03
#> [1781]  1.393935e-02  6.125872e-02  4.321480e-03 -2.515927e-03  3.077114e-02
#> [1786]  2.881368e-02  1.289528e-02 -1.882657e-03  8.394761e-03  1.532938e-02
#> [1791]  2.184522e-03  4.617074e-02  1.023445e-02  1.321298e-01  5.603237e-02
#> [1796]  7.345560e-02  2.001669e-03  2.966977e-02  5.563728e-02 -2.466357e-03
#> [1801]  2.089618e-02  7.382386e-03  2.176428e-02  1.561302e-02  2.647471e-03
#> [1806] -1.338972e-03  3.603297e-02  7.451421e-03  7.094577e-03 -3.330271e-04
#> [1811]  5.645596e-02  5.751397e-02  4.285314e-02  4.830163e-02  9.335939e-03
#> [1816]  1.814041e-02  1.814226e-02  3.722589e-02 -1.228427e-03 -1.557707e-03
#> [1821]  3.955922e-03  3.998132e-02  6.964887e-02  8.744290e-02 -5.963529e-04
#> [1826]  4.613966e-02  5.143227e-02  1.601083e-02  2.936431e-02  7.262785e-03
#> [1831]  2.034443e-02  1.339180e-02  2.653578e-03  1.213038e-02  2.228967e-03
#> [1836]  1.688835e-03  1.170200e-02  7.389821e-02  3.950661e-03  7.828968e-03
#> [1841]  3.397288e-03  1.109692e-02  4.594127e-03  7.815606e-03  1.888835e-03
#> [1846]  3.335877e-02  5.124890e-02  8.262367e-03  1.115615e-02  9.303076e-03
#> [1851]  5.201518e-03  2.621977e-03 -1.990703e-03  8.158520e-03  1.084553e-02
#> [1856] -1.670622e-03  1.779282e-02  7.115875e-03  5.189422e-02  1.050368e-01
#> [1861]  1.668553e-03  2.671201e-02 -2.244867e-03  6.440620e-02  2.489605e-02
#> [1866]  3.113932e-02  2.489430e-02  6.387611e-02  4.883468e-03  6.387380e-03
#> [1871]  7.494297e-03  2.538618e-04  2.801927e-02  2.865149e-02  5.533364e-03
#> [1876] -8.060748e-04  1.380123e-02  1.920269e-02  8.268674e-03  2.773548e-02
#> [1881]  1.919966e-04  2.844256e-03  1.631616e-02 -7.385874e-04  2.034442e-02
#> [1886]  2.625027e-03  3.429995e-02  5.532520e-02  5.005807e-02 -1.385768e-03
#> [1891]  4.570324e-02  1.138861e-02  1.931376e-02  4.334586e-02  4.316240e-03
#> [1896]  7.628218e-03  4.305916e-04 -1.360545e-03  1.298767e-01  1.972933e-02
#> [1901]  8.968302e-03  9.007771e-03  1.618158e-02  6.003453e-02  8.926226e-03
#> [1906] -6.663330e-04  1.890612e-02  2.806426e-02  1.000621e-02 -2.574010e-03
#> [1911]  9.315507e-03 -2.254965e-03  5.117149e-02  3.498304e-02  1.914845e-02
#> [1916]  5.194396e-04  8.460486e-04  1.091955e-02  9.637325e-03 -9.165182e-04
#> [1921]  3.691035e-02  1.383434e-03  3.071528e-03  4.281340e-03  9.056671e-03
#> [1926]  2.007237e-03  2.608583e-02  1.819515e-02  2.799998e-02  1.134087e-02
#> [1931]  2.330687e-02  2.060627e-02 -1.299609e-03  1.612155e-01 -2.358339e-03
#> [1936]  2.501028e-02 -1.742936e-03  1.027399e-02  5.585304e-03  4.427786e-03
#> [1941]  7.583667e-02  7.926514e-02  4.958996e-03  5.786751e-02  5.004664e-02
#> [1946]  2.555715e-02  6.588746e-02  1.533029e-03  7.069403e-02  4.834028e-03
#> [1951]  2.461864e-02 -1.821194e-03  3.285253e-02  1.646218e-02  3.306297e-03
#> [1956]  2.167379e-03  3.508180e-02  5.088904e-03  2.140037e-02  4.169344e-03
#> [1961]  5.441065e-03  1.007198e-02  3.838157e-03  2.566180e-02 -2.115178e-03
#> [1966]  1.143886e-02  1.535526e-03  1.615784e-03  1.243615e-02  2.965838e-03
#> [1971]  7.559727e-02  4.666659e-03 -2.639491e-04  1.980938e-02  1.299400e-02
#> [1976]  3.960284e-02  2.025274e-02  5.009958e-03  8.211657e-03 -3.081823e-04
#> [1981]  6.514795e-03  2.152836e-02  3.284910e-02  1.111605e-01  1.338167e-02
#> [1986]  5.016927e-02  2.830845e-02 -2.248083e-03  5.387904e-03 -2.490679e-03
#> [1991]  6.465019e-02  1.839794e-02  2.404400e-02  6.941532e-03  8.450119e-03
#> [1996]  2.069689e-02  2.371707e-02  2.428760e-02  4.519929e-02  2.122954e-02
#> [2001]  3.084701e-02  1.126980e-03  2.541225e-02  6.251572e-03  4.421079e-02
#> [2006]  1.910347e-02  3.382174e-03  4.783555e-02  1.091679e-02  2.101976e-02
#> [2011] -2.508915e-03  3.563032e-02 -6.886882e-04  2.848722e-02  8.238594e-03
#> [2016]  6.162869e-02  2.055231e-03 -2.601354e-03  2.189622e-03  3.780632e-02
#> [2021]  1.290309e-03  1.123745e-02 -1.550159e-03  2.043216e-02 -1.924227e-03
#> [2026]  3.811337e-03  2.104879e-02 -2.083376e-03  1.997152e-04  2.983340e-03
#> [2031]  1.049030e-02 -4.246094e-04  1.042042e-02  4.044657e-03 -1.038165e-03
#> [2036]  5.878506e-02  2.884799e-02  2.210792e-03  1.755952e-02  2.051809e-02
#> [2041]  1.344541e-02  1.819643e-02  4.740052e-02  2.616805e-02  1.579869e-02
#> [2046] -4.108953e-04 -2.308490e-03  2.425244e-02  2.674687e-02  7.578951e-03
#> [2051]  1.270090e-02 -2.232816e-03  2.958160e-02  7.202989e-02  9.019643e-02
#> [2056]  1.615553e-02  8.237616e-03  4.112227e-03  1.607333e-02  1.397729e-03
#> [2061]  1.567984e-02  2.459846e-02  1.518082e-03  1.506804e-02 -2.881424e-03
#> [2066]  1.777418e-02  7.238481e-03  1.751554e-02  7.807988e-03  5.076596e-02
#> [2071] -1.108706e-04  1.953192e-02  1.877432e-01  9.411776e-03  1.655205e-02
#> [2076]  1.258741e-02  5.180420e-03  1.428403e-02  9.897299e-02  9.383346e-03
#> [2081]  2.009348e-02  3.151050e-02  5.831663e-03  4.907977e-02  1.790472e-02
#> [2086]  2.109067e-02  3.336296e-03 -1.857974e-03  2.320993e-03  1.678149e-02
#> [2091] -2.473500e-03  3.353635e-03  1.206729e-01  2.972926e-02 -1.839308e-03
#> [2096]  1.416245e-02  1.872578e-03  4.772565e-02  2.898047e-02  1.159099e-01
#> [2101]  4.845939e-02 -1.030189e-04  1.284280e-03  6.980831e-02 -2.815539e-03
#> [2106]  4.377980e-02  4.798919e-03  1.273178e-02  3.557152e-02  1.701312e-02
#> [2111]  3.813414e-03  1.480783e-03  3.610905e-02  3.659838e-02  5.290277e-02
#> [2116]  2.693653e-02  1.238636e-02  6.824537e-03  4.933642e-03  5.796520e-03
#> [2121]  1.527643e-02  3.159403e-03  1.005599e-01  1.369484e-03 -7.033972e-04
#> [2126]  2.279429e-03  7.593609e-02  2.289419e-03  1.496203e-02  3.122831e-03
#> [2131] -1.817493e-03 -1.488606e-03  2.450313e-02  1.916261e-04  4.222158e-02
#> [2136] -1.688098e-03 -1.760771e-03  6.408142e-03  2.340646e-02 -2.849747e-03
#> [2141] -5.997621e-04  3.519041e-02  1.427143e-02  5.257487e-02 -1.802876e-03
#> [2146]  1.231204e-02  2.376041e-03  4.358487e-02  1.078885e-02  3.428759e-03
#> [2151] -2.615347e-03  1.194716e-02  5.069816e-03  1.211612e-02 -7.596945e-04
#> [2156]  1.469761e-02  2.367190e-03  3.264261e-03  4.666168e-02  5.352693e-02
#> [2161]  2.303973e-03  1.775766e-02  1.912665e-02  6.247345e-02  1.142240e-02
#> [2166]  8.232620e-03 -9.018534e-04  2.276461e-02  2.173550e-02  3.495629e-02
#> [2171]  3.064297e-02  1.235933e-02  5.600016e-02  2.521027e-02  1.928938e-02
#> [2176]  3.321081e-02  3.739623e-02 -5.031562e-04  8.026610e-03  2.027439e-04
#> [2181]  7.427240e-02 -1.561310e-03  3.361568e-02  5.403392e-03  8.990077e-03
#> [2186]  2.037010e-02  2.577938e-02  1.457466e-03  7.261764e-03  7.808967e-03
#> [2191]  7.414458e-02  2.821632e-03  7.552547e-03 -1.329490e-03  1.158914e-02
#> [2196] -8.676771e-04  2.389406e-02  1.507301e-02  3.469592e-02  1.960356e-02
#> [2201]  1.914004e-02  2.498771e-03  5.518699e-03  2.031682e-02  9.177856e-03
#> [2206]  2.139923e-02  7.602188e-02  5.520124e-02 -2.567068e-03  4.490127e-03
#> [2211]  6.204527e-02  5.125376e-02  2.529976e-02  3.051948e-02  3.780695e-02
#> [2216]  1.707060e-02  2.502639e-02  5.404542e-02  1.037564e-01 -1.602539e-04
#> [2221]  7.698135e-03  4.365226e-03  1.118888e-03  1.560500e-02  3.726831e-03
#> [2226]  1.488410e-02  6.713410e-02 -1.266605e-03  4.732127e-02 -5.259187e-04
#> [2231]  1.555321e-03 -7.768566e-04  1.043284e-02  1.450454e-02  1.379361e-03
#> [2236]  8.161092e-02  4.575294e-02  1.595353e-02 -8.057496e-04  4.954648e-02
#> [2241]  2.701268e-02  8.584276e-03  1.899270e-02  2.254054e-02  6.861052e-03
#> [2246]  1.601270e-02  6.111724e-03  5.446135e-03  1.093738e-02  1.158394e-01
#> [2251]  1.620705e-02  4.479455e-02  5.507709e-03  4.559179e-02  1.113623e-03
#> [2256]  3.607489e-02  2.589950e-03  1.830390e-02  1.806520e-02 -1.391996e-03
#> [2261]  1.086325e-01  4.796033e-03  3.851042e-03  6.109127e-02  6.394470e-03
#> [2266] -1.352937e-04 -1.938106e-03  3.377118e-02  6.262428e-03  1.379903e-04
#> [2271]  1.744777e-01  1.043928e-02  4.332678e-02  2.942606e-02  2.660514e-02
#> [2276]  3.335902e-03  8.817204e-04  2.103414e-03  5.519939e-02  6.253727e-03
#> [2281]  3.381549e-02  3.933747e-03  4.493471e-03  2.792193e-02  1.229615e-02
#> [2286]  3.512614e-02  9.491748e-03  1.297480e-02  2.619241e-02  3.696437e-02
#> [2291] -1.932089e-03  9.554452e-03  1.008385e-01  5.410704e-02  5.925991e-02
#> [2296]  3.431670e-03  4.555953e-02  2.792454e-03  2.311759e-03  2.752980e-02
#> [2301]  1.150874e-02  2.582307e-03  5.546213e-02  3.744571e-02  4.605537e-04
#> [2306]  1.622503e-03  7.470240e-03  3.918975e-03  1.917969e-02 -1.576896e-03
#> [2311]  1.976717e-02  2.021327e-02  7.710665e-03  2.053067e-03  1.767610e-02
#> [2316]  6.307332e-02  1.770809e-02  3.819625e-03  9.207384e-02 -1.138759e-03
#> [2321]  3.745193e-02 -2.371382e-03  7.737887e-03  2.881973e-02  2.805696e-02
#> [2326]  1.092690e-02  2.037138e-02  3.307111e-03  5.686443e-02  2.708142e-02
#> [2331]  8.008192e-03  9.957136e-03  7.538508e-02  7.030390e-02  1.133899e-02
#> [2336]  3.445135e-03  3.115222e-03 -5.082723e-04 -5.307123e-04  4.780514e-03
#> [2341]  2.299478e-02  6.814879e-02  4.391255e-02  6.283558e-03  2.102131e-02
#> [2346]  7.300584e-03  2.882781e-02  3.152010e-02  5.075830e-03  4.501171e-02
#> [2351]  2.749961e-03  7.945641e-03  2.308501e-02  9.266633e-03  7.726031e-03
#> [2356]  1.428617e-02  2.849836e-03  5.519681e-03  4.354491e-02  1.302360e-02
#> [2361]  1.484662e-03  3.475151e-03 -2.559362e-03  5.747419e-02  1.098003e-02
#> [2366]  3.187994e-02  7.954823e-03 -9.334179e-04  5.614293e-03  6.576080e-03
#> [2371]  1.112713e-02  9.472808e-03  6.897295e-03  9.045427e-02  1.728394e-02
#> [2376]  4.750716e-02  6.777200e-02  6.561033e-02  1.290795e-02  2.166785e-02
#> [2381]  6.265183e-03  9.427044e-03  2.328646e-02  5.976333e-02  1.641664e-02
#> [2386]  1.068121e-02  6.761181e-03  5.184065e-02  3.702597e-03  4.604538e-03
#> [2391]  2.103303e-02  1.339424e-02  8.671317e-03  4.831804e-02  1.668199e-02
#> [2396]  7.367508e-03  4.929348e-02  4.802063e-03  1.718312e-03  4.326819e-03
#> [2401]  3.459344e-02  1.842604e-03  2.508985e-02  2.031969e-03  3.661286e-02
#> [2406]  6.147350e-03  2.476693e-04  8.742907e-06  8.470099e-04  1.499853e-02
#> [2411]  7.326337e-02  4.850469e-03  7.496606e-03  6.190112e-03  6.843612e-03
#> [2416]  4.809009e-02  7.136920e-04  6.684095e-03  6.925736e-03 -1.535228e-03
#> [2421]  2.270977e-03  1.845611e-02  1.799817e-02  3.291532e-03  3.334974e-03
#> [2426]  5.432521e-03 -5.955088e-04  4.140001e-02  2.876280e-03  1.240586e-02
#> [2431]  5.639151e-04  1.651505e-02  2.593034e-02  4.109049e-03 -1.604350e-03
#> [2436]  2.763541e-02  2.637066e-02  1.533669e-02  9.162293e-03  2.294605e-02
#> [2441]  6.477404e-03  6.967089e-02  1.817793e-02  4.977052e-02  3.291764e-02
#> [2446]  4.033891e-02  3.422156e-03  1.889676e-02  2.919120e-03  7.103266e-03
#> [2451]  3.189637e-03  2.943892e-02  8.722944e-02  3.511448e-02  1.160954e-01
#> [2456]  1.471174e-02  2.674891e-02  4.249155e-03  4.694832e-02  1.000869e-01
#> [2461]  4.709825e-03  8.263585e-03  4.742046e-02  4.104828e-02  2.811622e-02
#> [2466]  5.003106e-02  3.947456e-02  1.400923e-02  2.683810e-02  6.304225e-03
#> [2471] -2.309687e-03  2.139563e-03  6.805131e-03  9.991695e-03  1.519231e-02
#> [2476]  2.451504e-02  3.374608e-02  9.308964e-03  3.118660e-03  4.880069e-02
#> [2481]  2.497233e-02  3.798265e-02  6.639519e-03  5.129893e-03  1.628761e-02
#> [2486] -3.197753e-04  6.948657e-02  6.562775e-02  1.568649e-01  7.126829e-03
#> [2491] -1.049964e-03  1.729669e-02  1.970722e-02  1.043923e-01  9.388966e-03
#> [2496]  4.210567e-02  3.092100e-02  1.168172e-01 -9.572585e-04  7.502781e-03
#> [2501]  5.476415e-02  1.075880e-02  7.173014e-03 -1.636332e-03  1.359090e-02
#> [2506]  1.868947e-02  3.512852e-02 -2.190298e-03  9.649761e-02  1.944205e-02
#> [2511]  3.386657e-02  8.377371e-03  1.655280e-02  4.011760e-02  2.804541e-03
#> [2516]  6.217952e-03  1.300348e-01 -2.921085e-03  7.770459e-03 -1.942073e-03
#> [2521]  2.068891e-02 -2.036245e-03  1.851231e-02 -4.723259e-04  4.780905e-02
#> [2526]  2.219720e-03  1.477824e-02  2.297715e-03  7.138903e-02  1.120337e-02
#> [2531]  8.222416e-03  2.306353e-02  9.909763e-03  1.075559e-02  2.043728e-03
#> [2536]  9.449394e-03  2.823577e-02  1.121972e-02  6.095628e-02  6.063859e-02
#> [2541]  6.444045e-03  3.823993e-02  3.058241e-02  9.684868e-03  2.657029e-02
#> [2546]  1.805235e-02 -2.548143e-03  3.495139e-02  2.723547e-02  3.525389e-03
#> [2551]  1.413145e-01  2.299897e-02  7.135589e-03  1.175469e-03 -1.306295e-03
#> [2556]  2.649531e-02  1.011676e-02  3.858908e-02  2.024597e-02  3.927774e-02
#> [2561]  1.782298e-03  6.902484e-02 -1.984969e-03  1.649867e-02  1.149997e-02
#> [2566]  1.363374e-02 -1.378607e-03  2.342442e-02  2.594709e-02  6.887291e-02
#> [2571] -2.094576e-03 -3.468140e-04  8.385425e-02  9.133077e-03  1.712599e-03
#> [2576]  7.544269e-04 -2.555290e-03  1.245904e-02  2.214145e-04  4.526691e-02
#> [2581]  2.217815e-02  6.936314e-03  3.599396e-03  9.643316e-03  2.160650e-03
#> [2586]  1.711496e-02 -3.122654e-04  5.917930e-02  9.998171e-03 -2.306338e-04
#> [2591]  6.058433e-02  6.317981e-05 -1.180184e-03  4.848614e-03  1.618887e-02
#> [2596]  3.017352e-03  1.218430e-02  2.443177e-02  6.276759e-02  5.093234e-03
#> [2601]  9.220901e-03  6.731597e-02  1.445113e-02  1.440232e-02  8.273099e-03
#> [2606]  8.419156e-03 -2.156679e-03 -2.630207e-03 -1.742665e-03  7.971420e-02
#> [2611]  1.088302e-03  5.291790e-03  8.786563e-03  1.604902e-02  6.331086e-02
#> [2616]  5.174021e-03  2.355309e-02 -1.496702e-03  5.621592e-03  1.726134e-02
#> [2621]  1.174701e-01 -1.026276e-03  1.255825e-01  1.881533e-02  5.984930e-04
#> [2626] -6.464974e-04  8.440495e-03 -1.365210e-04  1.715080e-02  5.824006e-03
#> [2631]  2.715063e-03  1.896431e-02  6.436195e-04  1.032351e-02  2.115796e-02
#> [2636] -5.867098e-04  4.482489e-03 -1.177522e-03 -5.687925e-04  1.612195e-02
#> [2641]  3.071990e-03  1.046080e-02  2.794392e-03  9.620853e-03  6.810059e-03
#> [2646]  1.146345e-02  1.023501e-01  2.597373e-02 -1.593743e-03  1.890011e-01
#> [2651]  6.440872e-04  9.890674e-03  2.116281e-03  1.212156e-02  9.675206e-04
#> [2656]  2.767082e-03  3.170968e-02  4.762396e-02 -8.548847e-04  1.913859e-02
#> [2661]  1.455301e-01  2.298390e-03  2.169884e-02  1.979122e-02  1.115148e-02
#> [2666]  2.948705e-02  3.630699e-02  2.594874e-02  4.905687e-02  7.291371e-02
#> [2671]  1.334915e-01 -1.882486e-04  1.722634e-02 -4.575687e-04  7.513745e-03
#> [2676]  1.687800e-02  3.898859e-03  5.918276e-02  1.319513e-02 -2.053394e-03
#> [2681]  1.682965e-03  1.653922e-02  4.330727e-03 -1.303559e-03  1.147607e-02
#> [2686]  2.091536e-02  3.961819e-02  1.429370e-02  4.107126e-02  2.806330e-02
#> [2691]  7.388909e-05  1.409693e-03 -1.444907e-03  8.918064e-03  1.364786e-02
#> [2696]  1.115895e-03  2.889369e-02  2.059482e-02  2.820011e-04  1.020394e-01
#> [2701]  9.526393e-03  8.449238e-03  7.233676e-02  2.424783e-02  1.036660e-01
#> [2706] -1.961006e-03  1.275059e-02  3.238834e-03  6.041536e-03  1.004435e-01
#> [2711]  3.406623e-02  1.292328e-02  5.755347e-03  7.090672e-03  1.846493e-02
#> [2716]  6.143795e-02  1.844293e-02  2.898057e-02  2.510925e-02  2.525182e-02
#> [2721]  6.016285e-03  4.371938e-03  3.738991e-02 -2.331855e-03  1.683223e-02
#> [2726]  2.045505e-02 -2.809995e-03  4.973126e-02  2.864720e-02  1.500155e-02
#> [2731]  5.784147e-02  9.268822e-03  5.366043e-02  2.162338e-02  3.888066e-02
#> [2736]  1.515111e-02  5.552567e-02  2.646978e-03 -1.558561e-03 -1.778112e-03
#> [2741]  3.829992e-04  1.216342e-02 -8.943735e-04  5.584906e-03  1.759496e-02
#> [2746]  8.621819e-02 -3.155135e-04  2.897688e-03  3.095931e-03  2.447357e-02
#> [2751]  1.731134e-02  8.946085e-03  3.803065e-02  1.182042e-02  2.305369e-05
#> [2756]  8.946444e-03  1.240000e-02  1.213224e-02  3.423787e-02  1.921487e-02
#> [2761]  1.090673e-02  1.859501e-02  4.502763e-02  1.414625e-02  2.627970e-02
#> [2766] -2.323466e-03  5.381218e-02  5.044209e-02  1.195612e-02  6.395295e-03
#> [2771]  5.407986e-02  8.907414e-03  2.711931e-03  1.091251e-03  6.572821e-03
#> [2776]  4.369608e-02  7.558616e-02  9.260570e-03  1.856135e-02  4.023495e-02
#> [2781] -1.894546e-03  2.231126e-02  4.814209e-02  3.805192e-02  1.056671e-02
#> [2786]  1.255645e-02  4.181647e-02  3.062394e-02  2.943624e-02 -2.237511e-03
#> [2791]  5.172630e-02 -1.527490e-03  7.877344e-02  2.576322e-02  2.179591e-02
#> [2796]  3.681408e-03  6.224461e-03 -2.531995e-03  6.670002e-02  4.110915e-02
#> [2801]  6.677410e-03  1.220660e-02  5.427688e-02  2.731307e-02  2.960876e-02
#> [2806] -3.348124e-04  2.201045e-03  2.171384e-02  2.091401e-02  8.348229e-02
#> [2811]  2.002153e-04  8.661019e-03  2.849819e-02  5.940446e-02  4.020138e-03
#> [2816]  1.756204e-02  6.031263e-03  3.929384e-02  3.892358e-02  1.148758e-02
#> [2821]  3.065049e-03 -1.301708e-03  2.309206e-02  6.084621e-03  5.171203e-03
#> [2826] -4.956475e-04  2.135543e-02  4.785664e-03  2.294387e-02  2.359014e-02
#> [2831]  5.598851e-02  1.541072e-02  4.623510e-02  8.015652e-03  9.830304e-03
#> [2836]  5.819062e-03  9.096533e-03  1.385612e-02 -6.194052e-04  3.728969e-02
#> [2841]  3.803693e-03 -1.116753e-03  2.978501e-03  7.969056e-02  7.033901e-03
#> [2846] -2.203011e-03  1.766387e-03  6.258743e-03  2.764921e-03  3.325525e-02
#> [2851]  1.294417e-01  4.306575e-02  6.054623e-02  2.736076e-02  2.821262e-02
#> [2856]  2.003287e-03  3.510433e-02  5.979025e-02  8.276458e-03  2.208649e-02
#> [2861]  1.495915e-02 -9.022610e-05  1.175849e-02 -8.082754e-04  1.171404e-02
#> [2866] -1.298432e-03 -8.236260e-05  8.607395e-04  8.034227e-02  1.068637e-01
#> [2871] -8.054628e-04  1.315393e-02  4.353600e-03  9.959923e-02  9.484952e-03
#> [2876]  3.113975e-02  4.916535e-03  1.560446e-02  3.063781e-02  4.983123e-02
#> [2881]  4.858560e-04  8.146301e-03  4.923855e-02  5.046823e-02  8.576627e-03
#> [2886]  2.103751e-02  7.021696e-02  1.632227e-02  1.309716e-02  1.713758e-02
#> [2891]  3.030387e-02  8.520954e-03  1.770375e-02  7.070626e-03  2.965416e-03
#> [2896]  4.347398e-02  2.173773e-03  4.359994e-02  4.835208e-03  2.036325e-02
#> [2901]  5.060968e-03  1.288993e-02  9.757849e-03 -1.715047e-03  1.814449e-02
#> [2906]  4.149227e-03  2.875386e-02  4.415830e-02  1.840517e-02  9.681103e-03
#> [2911]  2.483792e-02  1.024845e-03  3.778097e-02  1.545831e-02  6.640370e-02
#> [2916]  1.070397e-02  1.040023e-02  2.525324e-03  1.535845e-04 -2.602029e-03
#> [2921]  2.434291e-02  1.994439e-03  8.828136e-02  1.653963e-02  6.026849e-02
#> [2926]  9.463544e-02 -2.294269e-03  7.381128e-02  1.349733e-02  2.166846e-02
#> [2931]  1.364990e-02  2.508393e-02  8.868392e-03  9.347786e-02  1.373171e-02
#> [2936] -8.170957e-04  3.148618e-03  6.789243e-03 -2.453498e-03  1.181150e-01
#> [2941] -2.501603e-03 -2.876447e-03  3.501151e-03  3.093143e-03  2.401026e-02
#> [2946]  2.801394e-02  7.373462e-04  3.468860e-03  7.659084e-04  1.152107e-02
#> [2951]  1.182478e-02  1.460688e-03  4.781602e-02  2.278678e-02 -2.359528e-03
#> [2956]  2.699195e-02 -1.902305e-03  2.465521e-02  1.153284e-02  1.956544e-02
#> [2961]  6.001377e-03  1.782224e-02  4.707725e-03  2.706321e-02  1.014562e-03
#> [2966]  6.138777e-03  5.866025e-02  2.624293e-02  1.105976e-02  3.917855e-02
#> [2971]  2.862978e-02  4.450000e-02  2.666207e-02  8.111566e-03  2.691297e-02
#> [2976]  5.495446e-02  2.612010e-02  2.573284e-02  3.374491e-02  3.818765e-02
#> [2981]  6.425355e-03  7.566600e-02  1.072921e-02  3.364878e-02  4.890256e-03
#> [2986]  2.405005e-03  3.480822e-02  4.366262e-03  3.940973e-02  1.215127e-02
#> [2991] -2.644345e-03  4.754972e-02  1.602891e-02  6.996881e-03  2.395087e-02
#> [2996]  3.540222e-02  9.992748e-03  6.929208e-03  2.209249e-02  1.270535e-02
#> [3001]  5.769085e-02  1.557066e-02 -1.551389e-03  6.192846e-02 -2.569098e-03
#> [3006]  6.529163e-02  1.229034e-02  1.999039e-02 -1.072262e-03  1.611149e-02
#> [3011]  1.308548e-03  8.301365e-02  1.875237e-02  5.052781e-03  2.843971e-02
#> [3016]  1.541929e-03  1.778673e-02  2.530446e-03  2.262164e-02  8.113596e-03
#> [3021] -2.937065e-03  1.184221e-01  7.442226e-04  3.825156e-02  2.310091e-02
#> [3026]  2.871275e-02  1.034481e-02  3.836139e-02  4.801884e-03  1.810885e-02
#> [3031]  4.450766e-02 -2.900830e-03 -1.975767e-03 -1.775132e-03 -4.586852e-04
#> [3036]  1.229780e-02  3.029847e-03  1.112541e-02 -9.742940e-04  1.422618e-02
#> [3041]  3.974547e-02  4.492435e-03  9.646841e-04  2.532068e-04  1.968408e-02
#> [3046]  1.980404e-02  1.013499e-02  8.370402e-02  1.360370e-02  1.293382e-04
#> [3051]  1.037662e-02  3.219578e-02  2.406195e-02  7.615582e-02  2.474849e-02
#> [3056] -1.272086e-03  5.964608e-03  1.757342e-02 -1.665161e-03 -2.693269e-03
#> [3061]  8.411202e-02  1.532353e-02  1.683032e-02  6.876411e-04  1.014084e-02
#> [3066]  5.305951e-02  2.175426e-02  7.508494e-02  7.906679e-02  4.565822e-02
#> [3071]  4.973816e-02  1.989087e-02  2.059763e-03  1.285710e-02  3.217863e-03
#> [3076]  2.224198e-02  4.573089e-02 -1.269770e-03  1.867276e-02  2.133107e-03
#> [3081]  1.283002e-02  4.897750e-02  4.713789e-04  9.942251e-04  7.712680e-02
#> [3086]  3.601250e-02  3.184857e-03 -2.031035e-03  2.041408e-02  5.016261e-03
#> [3091]  2.505921e-02  4.035649e-02  6.079997e-02  1.159008e-01  4.332849e-02
#> [3096]  5.066886e-02  2.574705e-02  1.820681e-02  1.292478e-01  1.453810e-03
#> [3101]  9.208686e-03 -3.848160e-04  4.379483e-02  2.331419e-02  5.821772e-02
#> [3106]  8.199160e-03 -5.600509e-04  2.462250e-02  6.613519e-03  3.697485e-03
#> [3111]  2.266190e-02  1.565411e-02  6.563944e-02  5.838719e-02 -1.918202e-03
#> [3116]  2.201867e-02  3.694401e-02  5.535503e-03  1.944643e-02  5.682623e-03
#> [3121]  1.152037e-02  5.741302e-02  4.135718e-03 -1.379720e-03  6.087225e-02
#> [3126]  3.202361e-02  5.428699e-02 -1.926207e-03  4.203057e-03  1.160571e-03
#> [3131]  1.227696e-03  4.876135e-03  6.736531e-03  5.154947e-03  4.254198e-02
#> [3136]  2.094415e-02  2.317106e-04  1.200026e-02  6.813294e-02  5.748365e-03
#> [3141]  1.409206e-01  3.056140e-04  3.094415e-02 -8.188693e-04  2.222766e-03
#> [3146]  2.337810e-02  4.804695e-03  8.495099e-03  2.415282e-02  1.799327e-02
#> [3151]  2.114779e-02  5.423656e-02  2.257489e-02  1.740385e-02  1.201760e-02
#> [3156]  2.609157e-02 -3.885398e-04  1.169110e-02  1.401456e-02  2.677926e-04
#> [3161]  8.724781e-05  3.533727e-02  4.162564e-02  2.166806e-02  8.047786e-02
#> [3166]  1.124498e-02  4.330237e-02  6.399127e-03 -4.575687e-04  2.968203e-03
#> [3171]  6.321777e-02 -1.202400e-03  3.173611e-02 -2.563906e-03  1.600170e-02
#> [3176]  3.745513e-03  2.138391e-02  1.974278e-02  1.383615e-02  1.086671e-02
#> [3181]  3.830378e-02  1.036100e-03  5.970276e-03  2.865939e-02  2.218595e-03
#> [3186]  5.160481e-03  1.357441e-02 -7.704145e-04  1.871611e-02  1.463367e-02
#> [3191]  1.225920e-02  1.987239e-02  1.191140e-03  6.674729e-03 -2.516297e-03
#> [3196] -2.406448e-03  7.444471e-02  1.502587e-02  4.723098e-03  1.141242e-02
#> [3201]  1.622170e-02  2.132674e-02  3.420789e-02  4.502837e-02  9.906135e-03
#> [3206]  4.654977e-02  5.879084e-03  2.263739e-02  4.974132e-03  3.996121e-02
#> [3211]  4.626406e-03  2.972755e-03  3.093048e-02  1.439054e-02  9.967185e-02
#> [3216]  2.478754e-02  6.445073e-03  2.787099e-02  4.084851e-03  2.571495e-02
#> [3221]  1.432284e-01  1.992433e-02  5.176308e-02  8.450442e-02  1.349643e-01
#> [3226]  1.279259e-02  5.320303e-02  6.374667e-02  4.010820e-02  6.804738e-04
#> [3231]  3.808849e-02 -2.872359e-03  1.248906e-02  4.280092e-04  3.654456e-02
#> [3236]  1.806597e-02  3.997316e-02 -8.474965e-04  9.178522e-03  5.505488e-02
#> [3241]  4.401125e-03  1.416709e-02  2.641413e-02  2.045972e-03  9.080736e-02
#> [3246]  3.349956e-03  2.434307e-02  5.564643e-02  2.217463e-02 -1.524300e-03
#> [3251] -2.325198e-03  2.060222e-03  4.631584e-02  1.856217e-02  2.791788e-02
#> [3256]  1.948318e-02 -1.523742e-03  1.019438e-02  1.526828e-02  2.136349e-03
#> [3261]  3.487189e-02  6.450421e-02  2.476074e-03  1.409652e-02  2.233704e-03
#> [3266]  1.912392e-03 -2.536774e-06  2.004933e-02  4.716015e-02  2.937471e-02
#> [3271] -1.351888e-03  8.396819e-03  1.409984e-02 -2.836939e-03  5.772077e-02
#> [3276]  2.230220e-02  5.069708e-03  9.942206e-03  6.404973e-03  1.197802e-02
#> [3281]  1.147003e-02 -2.352757e-03  3.248761e-02  1.343171e-02  8.319172e-03
#> [3286]  2.350336e-02 -2.102828e-03  3.769910e-02  4.822230e-02  2.360693e-02
#> [3291]  4.330369e-02  5.125759e-03  1.591151e-01 -2.127256e-03  1.960460e-02
#> [3296]  5.740822e-02  3.196989e-02  2.961011e-03  1.440963e-03  3.888478e-02
#> [3301]  8.743047e-02  3.960757e-02 -2.727817e-03  3.691772e-02  7.317348e-03
#> [3306]  7.745880e-02  7.044227e-03  4.423317e-02  1.135932e-02  7.005162e-03
#> [3311]  2.155878e-03  3.564937e-02  2.539277e-02  1.511254e-03  1.906389e-02
#> [3316]  3.586916e-02  1.767745e-02  2.919503e-02 -2.277031e-03  1.406417e-02
#> [3321]  2.176831e-02  4.031619e-02  4.722221e-02  1.355952e-02 -1.859137e-03
#> [3326]  2.110070e-02  1.587382e-02  7.772062e-02 -5.858341e-04  2.237355e-03
#> [3331]  3.109894e-03  2.543425e-02  8.147119e-03  1.457259e-02  1.496321e-02
#> [3336]  5.721169e-02  5.467841e-02  5.142543e-03  1.948032e-02  6.770586e-03
#> [3341]  2.158177e-02  2.491858e-02  8.261176e-03  1.386538e-02 -6.094560e-04
#> [3346]  3.159154e-03  4.158394e-03  1.513505e-02  4.405868e-02  2.322118e-03
#> [3351]  1.307609e-02  5.943963e-02  1.827797e-02 -2.821985e-03  1.744261e-02
#> [3356]  2.198815e-02  2.216293e-02  3.176523e-03  1.755944e-02  5.506059e-02
#> [3361]  6.098281e-03  5.035442e-03  8.278225e-03  2.295382e-02  2.994840e-02
#> [3366]  5.525064e-02  1.957467e-02  2.969063e-02  6.126329e-02  1.577234e-02
#> [3371]  3.102709e-02  4.521843e-02  9.785028e-03  1.356951e-02  6.668984e-02
#> [3376]  3.451378e-02  1.224112e-02  2.114747e-02  1.285252e-02  3.518428e-02
#> [3381]  7.427530e-03  1.152382e-02  1.583107e-03  5.240005e-02  2.335532e-02
#> [3386] -2.428886e-03  1.691479e-02  5.470923e-03  2.104124e-02  2.271403e-02
#> [3391]  1.273358e-04  1.135728e-02  1.677426e-02  1.610888e-02 -2.570936e-03
#> [3396]  6.614669e-02 -1.957766e-03  1.029980e-01 -3.628570e-04  1.109559e-02
#> [3401]  3.241822e-02  1.047424e-02  3.711225e-03  1.280201e-02 -9.397205e-04
#> [3406]  1.910261e-02  2.046407e-02  5.061432e-05  2.671176e-02  1.080134e-02
#> [3411]  1.738916e-03 -1.782736e-03  6.896938e-03  2.468944e-02  1.539518e-01
#> [3416]  1.028658e-02  3.643844e-02  2.228478e-02  2.403515e-02  6.138756e-03
#> [3421]  1.177392e-02  6.261715e-03  4.059542e-02  2.356727e-02  2.385272e-02
#> [3426]  2.034472e-02  1.348821e-02  3.673163e-03  1.908641e-03 -2.739443e-04
#> [3431]  2.828204e-02 -2.524026e-03  1.238828e-02  2.833191e-02  1.272476e-02
#> [3436]  2.286051e-02  4.517000e-02  1.977585e-03  1.183799e-01  3.728075e-02
#> [3441]  1.424428e-03  1.358304e-02  9.700820e-04  2.980144e-03  3.837752e-02
#> [3446] -2.586294e-03 -1.423855e-03  3.899568e-02  1.048982e-02 -1.352750e-03
#> [3451]  8.913162e-03  2.497945e-02  6.885217e-03  5.320469e-03  3.678463e-02
#> [3456]  2.210135e-03  1.782895e-02  1.716133e-02  9.396676e-02  7.244224e-02
#> [3461]  1.381860e-02  5.270905e-02  1.357000e-02  2.742471e-02  2.458163e-02
#> [3466]  3.195343e-04  8.337699e-03  1.721793e-02  1.198915e-02  1.001194e-01
#> [3471]  1.581893e-02  7.046257e-02  6.023261e-02  7.046609e-02  2.446958e-02
#> [3476]  5.862417e-02  3.615487e-02  1.961007e-02  3.917661e-02  4.811140e-02
#> [3481]  2.224857e-02  1.344196e-02  1.803612e-02  1.789028e-02  3.975296e-02
#> [3486]  3.578970e-02 -1.926054e-03  3.890426e-02  2.815622e-03 -1.687716e-03
#> [3491] -2.529440e-03  8.551944e-03 -1.185529e-03  1.064760e-02  1.735263e-02
#> [3496]  3.008347e-02  8.697232e-03  1.471013e-01  5.742199e-04  3.494929e-03
#> [3501]  2.203641e-02 -2.945135e-04  5.829774e-02  7.201842e-03  1.189688e-03
#> [3506]  5.458149e-02 -2.152955e-03  5.375404e-03  2.358563e-02  1.363350e-02
#> [3511]  3.654386e-02  1.608243e-01  7.317608e-02  2.505359e-03  3.923557e-03
#> [3516]  3.670487e-02  6.142090e-03  7.701923e-03  6.125330e-02 -6.171507e-04
#> [3521]  3.359340e-02 -1.090318e-03  7.186315e-03 -2.354282e-03  2.457720e-02
#> [3526]  7.373876e-03  6.663109e-02  5.009064e-02  1.290036e-02  2.786064e-02
#> [3531]  1.887541e-02  8.729695e-03  1.274026e-02  4.762680e-03  2.656124e-02
#> [3536]  9.600928e-03  2.238670e-02  7.357543e-02  6.652324e-02  1.772345e-02
#> [3541]  3.126118e-02  9.717403e-03  1.234653e-02  2.621450e-02  2.999041e-04
#> [3546]  4.691506e-03 -5.999165e-04  1.891484e-02  1.473428e-02  1.139476e-02
#> [3551]  1.675783e-02  3.475234e-02  1.069972e-02  3.603964e-03 -2.394381e-03
#> [3556]  8.910168e-02  1.513421e-02  7.682592e-03  3.719108e-02  2.373465e-02
#> [3561]  4.557440e-03  7.790257e-02  5.211476e-02  2.729019e-02  1.102856e-04
#> [3566] -1.244166e-04  1.983509e-02  9.737978e-03  1.081303e-01 -6.938201e-04
#> [3571]  2.671733e-02  1.292202e-02  1.929320e-02  7.984716e-02  2.712946e-03
#> [3576] -2.919975e-03  4.525296e-02 -1.251791e-03  2.680897e-02  7.085635e-02
#> [3581]  2.267301e-02  7.263669e-02  7.303063e-03  5.680719e-02  7.496114e-03
#> [3586]  9.700027e-03  3.946642e-03  2.923525e-03  5.741969e-02  9.134057e-03
#> [3591]  6.517270e-03  2.472695e-02  1.022757e-01  3.216418e-02  1.304350e-02
#> [3596]  5.568184e-02  7.834264e-03  2.063482e-02  8.555949e-03  9.848411e-03
#> [3601]  8.868874e-02  9.254900e-02 -3.322815e-04  3.927496e-02  8.776905e-03
#> [3606]  3.856016e-02  1.794012e-02  5.705899e-02  1.465595e-02  1.211014e-02
#> [3611]  8.282277e-02  1.895266e-02  1.600368e-02  1.404340e-02  5.504990e-02
#> [3616]  4.075249e-02  3.881001e-02  4.595376e-02  1.975691e-02  1.636693e-03
#> [3621]  6.716231e-02  2.567995e-02  5.203016e-03  1.856143e-02  8.014979e-03
#> [3626]  2.967490e-02 -1.724435e-04  3.026381e-02  9.592824e-03  8.975599e-03
#> [3631]  3.959756e-03 -2.558948e-03  9.497891e-04 -1.193532e-03  1.460587e-02
#> [3636] -1.587173e-03 -4.490193e-04 -2.288946e-03  9.310783e-02  5.665414e-02
#> [3641]  1.419262e-02  7.563705e-02  1.159811e-02  4.021549e-03  5.878956e-03
#> [3646]  9.852494e-03  4.371296e-03  3.156065e-02  1.772556e-03  4.771247e-02
#> [3651]  1.252781e-02 -2.561811e-03 -1.865816e-03  4.254179e-02  3.099974e-02
#> [3656]  5.052944e-03  1.538072e-04  1.990621e-04  3.373917e-02  6.001233e-03
#> [3661]  5.394401e-02  3.270727e-02  1.048052e-02  2.543997e-02  1.461034e-02
#> [3666]  8.526336e-03  1.388970e-02  1.005153e-02  5.151102e-02  4.156820e-02
#> [3671] -9.807732e-04  7.043558e-02  8.774331e-02  8.412077e-02  2.292777e-03
#> [3676]  1.013366e-02  2.333159e-04  9.990326e-02  3.566318e-02 -6.327021e-04
#> [3681] -1.726803e-03  8.856110e-03 -9.694461e-04 -2.049072e-03  1.189462e-02
#> [3686]  2.071426e-02  1.374802e-02 -2.223897e-03  6.663751e-02 -1.205919e-03
#> [3691]  8.067771e-02  8.295856e-03  1.371299e-02  1.209536e-02  1.386409e-02
#> [3696]  2.047480e-02  2.713904e-02  4.893107e-03  8.554138e-03  9.337617e-02
#> [3701]  2.441249e-03  3.758047e-02 -3.889200e-04  8.335910e-03 -6.743212e-04
#> [3706] -2.398812e-03  1.187266e-02  1.223506e-02  5.429312e-02 -2.257972e-03
#> [3711]  7.029019e-04  2.648520e-03  5.852053e-03  4.695748e-02  3.355231e-03
#> [3716]  4.831463e-02  7.934225e-03  1.181485e-02  4.698302e-02 -1.058927e-03
#> [3721]  7.733015e-04  1.348861e-02  8.862422e-02  5.429009e-02  8.156819e-03
#> [3726]  7.596585e-03  3.829531e-03  4.299228e-02  2.608637e-02  4.488095e-02
#> [3731]  7.848212e-03  8.252625e-03  1.523382e-02  3.216146e-02  5.883908e-02
#> [3736]  3.183978e-04  3.887316e-02  2.304647e-03  3.783170e-02  3.326932e-02
#> [3741]  9.177659e-03  2.315245e-02  3.460127e-02  5.614293e-03  4.163099e-03
#> [3746]  8.536753e-02  1.709876e-02  2.062369e-02  2.815867e-02  1.030870e-01
#> [3751] -3.289727e-04  1.091449e-02  6.404196e-03 -1.873940e-03  1.697727e-03
#> [3756]  9.314150e-04  5.645485e-03  6.052984e-03  5.566210e-02  1.175984e-02
#> [3761]  7.331564e-02  2.814731e-02  8.623357e-03  4.643931e-04  1.028325e-02
#> [3766]  2.111154e-04  4.251821e-02  1.591601e-03 -1.409145e-03  5.963278e-02
#> [3771]  2.473784e-02  3.904296e-02  1.704233e-03 -6.878777e-04  4.524819e-02
#> [3776]  1.772504e-02  2.719731e-02  2.420507e-02  1.327039e-02  5.264173e-02
#> [3781]  1.027452e-02  7.564310e-03 -2.530397e-03  1.463048e-01  8.411158e-03
#> [3786]  9.265239e-02  1.713271e-02  3.914220e-03  1.754929e-02  7.428245e-03
#> [3791]  2.445407e-02  2.171564e-03  2.179275e-02  1.269184e-04  7.949253e-02
#> [3796]  5.947143e-03  7.899540e-03  1.213639e-03  6.623157e-03  5.387970e-02
#> [3801]  3.157161e-02  9.058358e-02  2.702407e-02  3.339702e-02  4.082794e-03
#> [3806]  1.014347e-01  1.370715e-02  8.777746e-02  5.756390e-02  1.410055e-02
#> [3811] -2.263631e-03  4.437683e-02 -6.591292e-04  3.004344e-03  2.627546e-02
#> [3816]  1.179525e-02  1.252151e-02  5.890052e-02  1.688866e-02 -2.358221e-03
#> [3821]  1.209644e-02  8.630318e-03 -1.569247e-04  3.037216e-02  2.869525e-02
#> [3826]  1.179456e-02  6.448595e-02  6.766988e-03  4.566995e-02  1.096180e-02
#> [3831]  6.513958e-03  5.942870e-03  7.795817e-03  1.152283e-02  1.178173e-02
#> [3836]  2.404145e-02  3.939307e-04  1.287368e-02  8.981096e-03  1.772088e-02
#> [3841]  1.235277e-02  3.357105e-02  4.917094e-02  8.120126e-02  7.151791e-03
#> [3846]  2.009375e-02 -1.069756e-03  2.535762e-03 -2.578595e-03  2.198733e-03
#> [3851]  5.451959e-03  1.390552e-03  1.419297e-02  1.909770e-03  7.063492e-03
#> [3856] -1.537435e-03  3.334640e-02  2.692454e-02  3.608179e-02  4.571727e-02
#> [3861]  1.510421e-02  7.030996e-02  1.046065e-02  3.359752e-02  1.379765e-01
#> [3866]  7.010466e-03  2.929714e-02  4.397438e-02  1.123653e-02  1.291202e-02
#> [3871]  1.098987e-02  8.971943e-03  1.375898e-02  8.271952e-02  8.638031e-04
#> [3876]  3.356881e-03  2.338373e-03  5.927493e-03 -1.852201e-03  7.809487e-02
#> [3881]  2.099281e-02  1.406024e-02  7.445652e-02  1.327070e-02 -2.219403e-03
#> [3886]  3.256528e-02  2.601754e-02  1.971020e-02  7.665938e-03 -1.306313e-03
#> [3891]  5.601717e-02  3.686143e-03  3.292465e-03 -1.660648e-03  7.275627e-03
#> [3896] -1.632911e-03 -7.381453e-05  3.955558e-02  1.170909e-02  2.945224e-02
#> [3901]  9.060673e-03  1.899527e-02  6.664491e-03  2.194438e-02  1.122455e-02
#> [3906]  3.056846e-02  2.724983e-02  1.782221e-02  1.854764e-02  1.081567e-02
#> [3911]  6.648866e-03  1.914963e-02  3.551554e-02  8.165104e-03  3.921673e-03
#> [3916]  2.356407e-02  1.472712e-02  7.279717e-03  4.917503e-02  1.804181e-02
#> [3921]  6.596441e-03  3.763088e-04 -1.451748e-03  8.322944e-04  1.425380e-02
#> [3926] -1.574063e-03  3.354150e-03  4.686176e-02  2.717359e-03  5.747680e-02
#> [3931]  2.924942e-02  2.546594e-03  3.223159e-02  9.333504e-03  4.637828e-02
#> [3936]  4.989516e-03  5.199421e-02  1.541692e-02 -1.692902e-03  4.051424e-02
#> [3941]  4.734731e-02  1.816573e-02  4.482951e-02  9.601372e-03  6.507318e-03
#> [3946]  3.769564e-03  5.039817e-03  3.877294e-02  1.459227e-02  2.119629e-03
#> [3951]  1.963136e-02  5.782959e-02  1.377326e-03  1.609469e-02  9.813347e-04
#> [3956]  2.452060e-02  3.001135e-02  1.115801e-02  3.808289e-02  1.707053e-02
#> [3961]  5.543394e-03  4.217639e-02  6.016287e-02  2.079317e-02  1.926422e-02
#> [3966]  2.028217e-03  5.522516e-03  6.345784e-04 -1.179407e-04  5.640892e-02
#> [3971]  1.048131e-02  4.580649e-04  5.219761e-02  1.408270e-02  1.513188e-02
#> [3976]  5.230197e-02  2.265936e-02  4.595929e-03  1.119041e-02  5.623666e-02
#> [3981]  1.425426e-02  2.051126e-02  3.646850e-03  5.951764e-02 -1.121876e-03
#> [3986]  1.789230e-02 -2.477517e-04  2.064505e-02  9.361977e-03  2.573416e-02
#> [3991]  4.811381e-02  3.126665e-02  1.381423e-03  1.377014e-03  1.490805e-02
#> [3996]  1.299228e-03 -1.097513e-03  3.912417e-02  8.777437e-02  9.426664e-03
#> [4001]  6.640506e-02  1.827580e-04  3.409692e-02  1.160279e-02  8.960894e-03
#> [4006]  1.339878e-02  1.181833e-02 -7.225670e-04  5.540043e-03  3.575652e-02
#> [4011]  4.304136e-04  2.991193e-02  7.285191e-03  1.931436e-02  2.390143e-02
#> [4016]  6.364382e-02  1.326719e-01  5.743384e-03  3.956606e-02 -1.946163e-03
#> [4021] -1.843147e-03  2.908634e-02  1.938187e-02  2.050227e-02  3.002657e-03
#> [4026]  2.002148e-02  1.448923e-02  5.174523e-02  1.274837e-02  1.903947e-02
#> [4031]  2.593251e-02  7.863033e-03  2.966907e-02  1.360091e-02  3.510552e-02
#> [4036] -7.434177e-04  3.678743e-02  6.228696e-02  4.354420e-02  2.770500e-02
#> [4041] -1.060069e-03  1.385282e-02  2.154217e-02  3.911874e-02  8.424684e-02
#> [4046]  2.720660e-02  2.568220e-02  6.190314e-03  1.095827e-01  4.270212e-02
#> [4051]  1.357675e-02  1.534353e-02  1.864263e-04  3.886007e-02  1.487800e-02
#> [4056]  4.238729e-02  1.120259e-01  2.105411e-02 -4.632134e-05  5.035771e-03
#> [4061] -1.155601e-04  1.736437e-03  3.570575e-02  2.094476e-02  1.496412e-02
#> [4066]  9.614305e-02  1.414392e-02 -1.290408e-03  1.993799e-03  2.617178e-02
#> [4071]  3.784032e-02  7.908867e-03  8.219337e-04  1.975109e-02  3.231588e-03
#> [4076]  1.560735e-03  4.137022e-03  9.535088e-03  1.206655e-02  3.730378e-03
#> [4081]  6.562153e-02  2.109476e-02  4.572186e-02  1.291920e-02  5.990025e-02
#> [4086]  3.487805e-03  1.098354e-02  1.317497e-02  7.282498e-02  3.552721e-03
#> [4091]  1.938864e-02  2.323828e-02  2.717995e-02  2.027514e-02  6.544030e-04
#> [4096]  2.834599e-02  3.362681e-03  1.507149e-03  1.317171e-02  5.752095e-02
#> [4101]  5.963033e-03  1.952886e-02  1.272115e-02  2.716299e-02  5.217431e-02
#> [4106]  1.260335e-03  4.080805e-03  4.456099e-03  4.571284e-03  1.644601e-03
#> [4111]  7.632721e-03  2.085298e-02  1.341679e-02  1.215896e-03  3.375068e-02
#> [4116]  2.040508e-02  6.023559e-02  5.899042e-03  6.020574e-03  4.783715e-02
#> [4121] -1.199709e-03  2.670826e-02  1.077113e-02  4.824778e-03  2.864573e-02
#> [4126]  7.405571e-02  1.858652e-02 -1.848169e-03  4.063753e-02  1.662070e-03
#> [4131]  3.893436e-02 -1.347181e-03  2.313814e-03  3.680185e-02  2.869437e-02
#> [4136]  1.961657e-02  2.199134e-03  9.624059e-02  2.169917e-02  1.506119e-02
#> [4141]  5.020983e-02  1.881312e-02  4.709557e-02  6.574353e-03  1.778481e-02
#> [4146]  5.374333e-03  5.743333e-02  5.942204e-02  3.965048e-02  1.812033e-02
#> [4151]  3.936088e-02  1.533236e-03  1.058909e-02  3.109443e-02  1.293436e-02
#> [4156]  2.286678e-02  3.232518e-02  4.436179e-02  1.279209e-02  2.099512e-02
#> [4161]  8.431990e-03  3.142981e-02  7.683255e-02  7.882065e-03  2.706860e-02
#> [4166]  1.303003e-02  1.888057e-02  7.419545e-02  6.342035e-03 -5.468802e-04
#> [4171]  6.654812e-02  4.845625e-04  1.912677e-02  1.320609e-02  1.216692e-02
#> [4176]  1.021558e-01  8.892672e-03  1.458124e-02  5.329934e-02  5.511953e-03
#> [4181] -1.980631e-03  1.591285e-04  2.723724e-02  3.478530e-02  4.814252e-02
#> [4186]  1.166673e-02  8.672777e-03  5.675040e-02  6.513449e-02  2.052194e-02
#> [4191] -1.943701e-03  3.532260e-02  4.427894e-02  5.769570e-02  2.026432e-02
#> [4196]  2.806021e-02  1.117699e-02  4.051922e-03  7.089216e-03  5.183717e-04
#> [4201]  4.915222e-03 -8.139908e-04  1.144296e-02  1.058608e-01  1.940011e-02
#> [4206]  1.196029e-02  4.990570e-02  1.810423e-02  3.943977e-03  4.942626e-03
#> [4211]  3.038254e-03  1.416346e-02  6.702244e-03  1.341664e-04  7.547500e-02
#> [4216] -6.014181e-04  3.670711e-05  1.759949e-03 -1.229356e-03  1.915625e-02
#> [4221] -2.029021e-03  7.302329e-02  3.766510e-02  6.470291e-03  1.305876e-02
#> [4226] -9.686190e-04  4.797929e-02  1.350881e-01  6.545475e-03  2.153669e-02
#> [4231]  2.011700e-02  3.983772e-02 -2.419998e-03  4.216496e-02  3.329030e-02
#> [4236]  3.896045e-02  3.036439e-02  2.896083e-03  7.314771e-03  1.104076e-01
#> [4241]  5.751002e-03  1.029692e-02  1.333281e-02  4.781886e-02  8.756499e-02
#> [4246]  5.065722e-03  3.922001e-02  5.095013e-03  4.183715e-02  6.611289e-03
#> [4251]  1.269184e-02  5.374595e-02  1.157931e-02  1.822334e-02  7.222208e-03
#> [4256]  3.235236e-04  9.645320e-03 -2.407953e-03  2.333372e-02  5.083638e-03
#> [4261]  1.514201e-01  2.006783e-02  3.222357e-02 -9.040444e-04  6.437826e-03
#> [4266]  3.692124e-03  2.952207e-03  4.991981e-02  1.345071e-02  1.109476e-01
#> [4271]  9.677391e-03  4.271158e-02  2.259543e-02  1.185627e-02 -2.349847e-03
#> [4276]  3.353035e-02  4.796677e-03  1.103392e-01  2.958458e-02  1.130254e-01
#> [4281]  5.976819e-02  1.322971e-02  3.092407e-02  8.046309e-03  2.406551e-03
#> [4286] -1.795244e-04  3.369684e-02  1.841724e-02  1.642253e-02 -6.893293e-04
#> [4291]  2.038404e-02  4.162813e-03  3.093811e-02  6.932805e-04  1.174744e-02
#> [4296]  1.732358e-03  2.438705e-03  2.200888e-02  1.377901e-02  3.429776e-02
#> [4301]  7.640385e-03  9.380366e-04  1.178943e-03  5.586516e-02 -1.425256e-03
#> [4306]  2.070561e-02  5.636104e-02  6.787557e-03  2.892089e-02  2.210099e-02
#> [4311]  3.208127e-02  1.468335e-02  2.794074e-02  2.733372e-03  7.118502e-03
#> [4316] -1.841767e-03 -1.680863e-03  2.512369e-02 -8.392539e-04  8.141580e-02
#> [4321]  2.527296e-02  1.821565e-02 -1.745169e-03  2.034212e-02  6.419717e-03
#> [4326]  7.910655e-03  3.177992e-02  1.653363e-02  9.743475e-03  2.589877e-02
#> [4331]  1.342946e-02  1.355253e-03  8.238393e-02 -2.938918e-03  2.370014e-02
#> [4336]  4.313940e-03  3.279517e-03  2.561416e-02  1.733366e-02  5.605311e-02
#> [4341]  1.436891e-02  1.649961e-03  5.898163e-02  2.175300e-02  4.961497e-02
#> [4346]  1.890928e-02  4.756537e-02  7.938607e-02  1.961278e-02  7.909242e-02
#> [4351]  8.542239e-03  3.118053e-03  6.232466e-02 -1.450790e-03  2.715324e-02
#> [4356] -2.341138e-03 -2.323003e-03 -2.857275e-03  1.505079e-02  2.106345e-03
#> [4361]  3.984836e-03  3.427851e-03  1.329513e-02 -1.459649e-03  4.210641e-02
#> [4366] -2.835040e-03  3.889919e-02  1.173550e-02  3.600537e-02  1.050153e-01
#> [4371]  3.298921e-02  3.881414e-02 -2.933260e-03 -2.307766e-03  1.043930e-01
#> [4376]  6.398031e-03  3.769073e-03  3.790882e-03  2.127794e-02  3.127251e-02
#> [4381] -3.628298e-04  5.607837e-03  4.181641e-02  3.985262e-02  3.292462e-02
#> [4386]  5.916952e-04  8.832809e-03  1.566461e-02  2.104766e-02  4.680259e-02
#> [4391] -1.139975e-03  1.110287e-01  6.306620e-04  1.212220e-01 -2.274275e-03
#> [4396]  1.281579e-03 -5.590555e-04  7.958714e-02  1.025728e-02  3.928318e-02
#> [4401]  6.807846e-02  1.049371e-01  3.504400e-02  2.863423e-02  1.987341e-03
#> [4406]  3.192475e-02  2.070630e-02  3.765141e-02 -1.541979e-03  5.487713e-02
#> [4411]  3.851719e-02  1.739025e-02  4.506979e-02  2.677126e-02  9.075934e-03
#> [4416]  8.365458e-02  1.741704e-02  1.760870e-02  1.106575e-02  6.761821e-02
#> [4421]  1.133193e-02  3.026451e-02  1.444981e-01  8.621335e-03  2.563390e-02
#> [4426]  3.229623e-02  1.980353e-02  3.370774e-02  2.833270e-02  5.934352e-03
#> [4431]  1.471317e-02  4.647459e-02  2.485961e-02  3.059991e-03  1.363358e-03
#> [4436]  5.859500e-03  6.359869e-02  2.605877e-03  2.046598e-02  4.521846e-02
#> [4441]  5.160040e-03  3.056564e-03  1.259718e-04 -3.585183e-04  1.656425e-03
#> [4446]  3.278588e-03 -1.712937e-03 -1.370717e-03  1.069524e-02  4.891732e-02
#> [4451]  3.681946e-04  3.418503e-02  2.753701e-02 -2.505408e-03  8.202462e-03
#> [4456]  1.261531e-02  2.338456e-02  4.110376e-03  7.259566e-04  2.011013e-02
#> [4461]  3.997383e-02  5.962014e-03  5.679034e-04  3.912512e-02  1.891997e-02
#> [4466]  3.923447e-02  1.143429e-02  1.836384e-02  2.076667e-02  7.554368e-02
#> [4471]  3.000659e-02  2.076154e-02  8.341093e-03  6.547932e-03  9.458714e-03
#> [4476]  3.744092e-02  1.415350e-03  8.424903e-03  9.563811e-03  3.294141e-02
#> [4481]  2.620042e-03  1.154122e-01  5.721456e-02  3.456534e-02 -2.679825e-03
#> [4486]  2.455328e-02  3.216031e-02 -2.368877e-03  3.643991e-02  3.422972e-02
#> [4491]  1.075779e-02  8.439185e-02  1.398260e-02 -1.491459e-03  2.408355e-03
#> [4496]  1.361067e-02  7.247190e-03 -8.002589e-04  3.054399e-02  1.879555e-02
#> [4501]  7.740688e-03  6.150323e-03  1.117753e-02  3.427531e-03  1.353836e-02
#> [4506]  4.000724e-02  3.442725e-02  4.215573e-03  1.006971e-03  1.754639e-02
#> [4511]  6.979137e-03  5.864168e-02  1.024358e-03  4.645030e-02  3.741620e-02
#> [4516]  1.090775e-02  2.220297e-03 -7.175973e-04  1.230743e-02  3.593143e-02
#> [4521]  2.442180e-02  2.134318e-02  3.927298e-02  1.893632e-02 -2.067187e-03
#> [4526]  7.407426e-02  1.118588e-02  3.739736e-02  3.742153e-02  6.079512e-03
#> [4531]  5.507471e-02  1.000590e-03  1.526019e-02  3.778144e-02  1.332125e-02
#> [4536]  5.211144e-03  4.739557e-02  1.326923e-02  5.188253e-02  2.051836e-02
#> [4541]  3.271079e-03  1.507747e-02
snp_fst(list_df_af[c(1, 2)], overall = TRUE)
#> [1] 0.02266401
snp_fst(list_df_af[c(1, 3)], overall = TRUE)
#> [1] 0.03573594
snp_fst(list_df_af[c(3, 2)], overall = TRUE)
#> [1] 0.01381693