Creates a quantile-quantile plot from p-values from a GWAS study.
snp_qq(gwas, lambdaGC = TRUE, coeff = 1)
A mhtest
object with the p-values associated with each SNP.
Typically, the output of big_univLinReg, big_univLogReg or snp_pcadapt.
Add the Genomic Control coefficient as subtitle to the plot?
Relative size of text. Default is 1
.
A ggplot2
object. You can plot it using the print
method.
You can modify it as you wish by adding layers. You might want to read
this chapter
to get more familiar with the package ggplot2.
set.seed(9)
test <- snp_attachExtdata()
G <- test$genotypes
y <- rnorm(nrow(G))
gwas <- big_univLinReg(G, y)
snp_qq(gwas)
gwas_gc <- snp_gc(gwas) # change attr(gwas_gc, "transfo")
snp_qq(gwas_gc)
# The next plot should be prettier with a real dataset
snp_manhattan(gwas_gc,
infos.chr = test$map$chromosome,
infos.pos = test$map$physical.pos)
p <- snp_qq(gwas_gc) + ggplot2::aes(text = asPlotlyText(test$map))
if (FALSE) plotly::ggplotly(p, tooltip = "text")